Table 1:
Baseline characteristics of FHN Trial participants who had baseline sodium concentration values
| Characteristic | N (available data for respective parameter ) |
3X Daily Pts (N=98) |
3X Daily Pts with SNa=<138 mEq/L (N=46) |
3X Daily Pts with SNa>138 mEq/L (N=52) |
N (available data for respective parameter ) |
6X Daily Pts (N=99) |
6X Daily Pts with SNa=<138 mEq/L (N=50) |
6X Daily Pts with SNa>138 mEq/L (N=49) |
|---|---|---|---|---|---|---|---|---|
| Age (yrs.) | 98 | 52.1 ± 12.7 | 52.9 ± 12.8 | 51.3 ± 12.7 | 99 | 48.7 ± 12.7 | 48.2 ± 12.6 | 49.1 ± 12.8 |
| Female (%) | 98 | 38 (39%) | 21 (40%) | 17 (37%) | 99 | 38 (38%) | 23 (47%) | 15 (30%) |
| Race | 98 | 99 | ||||||
| Black (%) | 44 (45%) | 18 (35%) | 26 (57%) | 40 (40%) | 18 (37%) | 22 (44%) | ||
| White (%) | 34 (35%) | 22 (42%) | 12 (26%) | 32 (32%) | 16 (33%) | 16 (32%) | ||
| Native American, Aboriginal Canadian, Alaskan | 4 (4%) | 3 (6%) | 1 (2%) | 4 (4%) | 1 (2%) | 3 (6%) | ||
| Native (%) | 5 (5%) | 3 (6%) | 2 (4%) | 9 (9%) | 4 (8%) | 5 (10%) | ||
| Asian (%) | 3 (3%) | 3 (6%) | 0 | 1 (1%) | 0 | 1 (2%) | ||
| Native Hawaiian or other Pacific Islander (%) | 8 (8%) | 3 (6%) | 5 (11%) | 13 (13%) | 10 (20%) | 3 (6%) | ||
| Other/mixed/unknown (%) | ||||||||
| Ave. Weekly Predialysis Systolic BP (mmHg) | 98 | 146 ± 18 | 146 ± 20 | 145 ± 17 | 99 | 148 ± 17 | 149 ± 17 | 147 ± 18 |
| Ave. Weekly Predialysis Diastolic BP (mmHg) | 98 | 78.1 ± 11.0 | 77.6 ± 10.5 | 78.7 ± 11.7 | 99 | 81.7 ± 11.4 | 82.4 ± 9.1 | 80.9 ± 13.3 |
| Ave. Weekly Postdialysis Systolic BP (mmHg) | 98 | 133 ± 18 | 133 ± 18 | 133 ± 17 | 99 | 135 ± 19 | 135 ± 18 | 135 ± 20 |
| Ave. Weekly Postdialysis Diastolic BP (mmHg) | 98 | 71.6 ± 10.3 | 70.4 ± 9.3 | 72.9 ± 11.3 | 99 | 73.7 ± 11.6 | 74.4 ± 10.7 | 73.0 ± 12.5 |
| Left Ventricular Mass (g) | 98 | 145 ± 52 | 147 ± 55 | 143 ± 49 | 99 | 146 ± 58 | 139 ± 50 | 152 ± 64 |
| Left Ventricular End-diastolic Vol. (ml) | 98 | 184 ± 70 | 188 ± 60 | 179 ± 80 | 99 | 179 ± 57 | 177 ± 48 | 181 ± 65 |
| Extra-cellular fluid volume (L) | 97 | 22.9 ± 4.7 | 23.0 ± 4.6 | 22.9 ± 5.0 | 94 | 22.7 ± 4.2 | 22.7 ± 4.1 | 22.7 ± 4.4 |
| Extra-cellular fluid volume / Total Body fluid volume (L) [BIA] | 97 | 0.528 ± 0.063 | 0.530 ± 0.066 | 0.525 ± 0.060 | 94 | 0.517 ± 0.073 | 0.530 ± 0.069 | 0.505 ± 0.075 |
| Extra-cellular fluid volume / Ave. Weekly Postdialysis Wt. | 97 | 0.298 ± 0.040 | 0.301 ± 0.043 | 0.294 ± 0.036 | 94 | 0.298 ± 0.045 | 0.301 ± 0.046 | 0.294 ± 0.045 |
| IDWG (% post HD body weight) | 88 | 4.21 ± 1.30 | 4.64 ± 1.38 | 3.75 ± 1.03 | 85 | 4.25 ± 1.36 | 4.43 ± 1.46 | 4.09 ± 1.27 |
| IDWG (% of ECV) | 88 | 14.2 ± 4.0 | 15.5 ± 4.1 | 12.8 ± 3.4 | 82 | 14.5 ± 4.8 | 14.9 ± 4.4 | 14.1 ± 5.2 |
| time-integrated fluid load (TIFL; units liter × day) | 88 | 4.74 ± 2.06 | 5.71 ± 2.05 | 3.69 ± 1.50 | 82 | 4.72 ± 2.33 | 5.57 ± 2.54 | 3.99 ± 1.88 |
| Body Mass Index (kg/m2) | 97 | 28.8 ± 7.2 | 28.7 ± 6.7 | 28.8 ± 7.7 | 94 | 28.9 ± 6.5 | 28.7 ± 7.0 | 29.0 ± 6.1 |
| Predialysis Bicarbonate (mEqL) | 98 | 23.7 ± 4.2 | 22.4 ± 4.5 | 25.2 ± 3.5 | 99 | 23.9 ± 3.3 | 23.7 ± 3.5 | 24.1 ± 3.0 |
| Diabetes (%) | 98 | 40 (41%) | 26 (50%) | 14 (30%) | 99 | 39 (39%) | 23 (47%) | 16 (32%) |
| Left Ventricular Ejection Fraction (%) | 98 | 56.2 ± 12.4 | 55.4 ± 12.7 | 57.0 ± 12.2 | 99 | 57.8 ± 10.0 | 57.7 ± 10.3 | 57.9 ± 9.8 |
*
Plus-minus values are means ±SD. Bracketed values are medians with interquartile ranges.