Table 2:

Individual subject results of fMRI BOLD responses to speech in the canonical language network

		ROI
		IFG Left	IFG Right	STG Left	STG Right
Healthy Subjects
1		+	+	+	+
2		+	+	+	+
3		−	−	+	−
4		+	+	+	+
5		+	−	+	+
6		+	−	+	+
7		+	+	+	+
8		+	+	+	+
9		+	+	+	+
10		+	+	+	+
11		+	+	+	+
12		−	−	−	+
13		−	+	+	+
14		+	+	+	+
15		+	+	+	+
16		+	+	+	+
Patients
1	Acute*	+	+	+	−
	Follow-up	+	−	+	−
2	Acute	+	+	+	+
	Follow-up	+	+	+	+
3	Acute*	−	−	−	−
	Follow-up	−	−	+	+
4	Acute	−	−	−	−
	Follow-up	+	+	+	+
5	Acute*	−	+	+	−
	Follow-up	−	−	+	+
6	Acute*	−	+	−	−
	Follow-up	+	+	+	+
7	Acute*	−	−	+	+
	Follow-up	+	−	+	+
8	Acute*	+	−	+	−
	Follow-up	+	+	+	+

For each subject and each ROI, a “+” indicates that an fMRI BOLD response to speech was detected while a “−“ indicates that an fMRI BOLD response to speech was not detected. In all healthy subjects, responses were detected in right, left or bilateral STG. In 14 healthy subjects, responses were detected in right, left or bilateral IFG. No IFG response were detected in 2 healthy subjects. In 5 patients, responses were detected in right, left or bilateral STG acutely and in all 8 patients, responses were detected in right, left or bilateral STG at follow-up. Similarly, in 5 patients, responses were detected in right, left or bilateral IFG acutely. In 6 patients, responses were detected in right, left or bilateral IFG at follow-up

^{* =}patient received sedative, anxiolytic, or analgesic medication before or during the acute functional MRI (see Supplemental Material, Table S5 for specific medications and doses).