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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Cancer. 2021 Sep 1;128(1):180–191. doi: 10.1002/cncr.33879

Table 3.

Among survivors with seizure, effect of seizure resolution and seizure severity on social attainment outcomes.

Outcomes Measure CNS survivors Non-CNS survivors
Seizure Presence Seizures resolved Seizure Severity Seizure Presence Seizures resolved Seizure Severity
RR 95% CI RR 95% CI RR 95% CI RR 95% CI RR 95% CI RR 95% CI
Marital Status Single or Never married 1.02 0.95,1.09 0.85 0.76, 0.97 0.93 0.81,1.05 1.03 0.97,1.08 0.95 0.85,1.07 1.03 0.92, 1.15
Married/Living as married 1.0 1.0 1.0 1.0 1.0 1.0
Education (< college graduate) 0.98 0.92,1.05 0.95 0.84,1.08 0.91 0.80,1.02 1.02 0.97,1.07 0.99 0.89,1.09 1.04 0.94,1.15
College graduate 1.0 1.0 1.0 1.0 1.0 1.0
Employment (part time or unemployed) 1.09 1.01,1.18 0.88 0.78,1.00 0.94 0.81,1.09 1.11 1.05,1.17 0.83 0.74,0.93 1.02 0.91,1.15
Full time employment 1.0 1.0 1.0 1.0 1.0 1.0
Household income (<$40,000) 0.98 0.88,1.08 1.01 0.85,1.19 0.95 0.79,1.13 1.02 0.96,1.08 0.93 0.82,1.06 0.98 0.87,1.10
Household income (≥$40,000) 1.0 1.0 1.0 1.0 1.0 1.0

Seizures resolved refers to yes vs. no. Seizure severity was scored as ≥3 (most severe) vs. <3 (less severe) in the past. For CNS, covariates included age, sex, brain radiation yes vs no; for non-CNS, covariates included age, sex, brain radiation dose group (none, <24 Gy, ≥24 Gy), high dose methotrexate, and intrathecal methotrexate. Bold indicates significant relative risk.