Figure 1. Body Weight, Body Composition, and Insulin Resistance in Obese and Non-obese mice.
Mice were fed LFD (n=19) or HFD (n=20) from 6 weeks until 26 weeks of age (20-week duration). (A) Body weight, fat mass and lean mass after 20 weeks of diet. Statistical differences were assessed by two sample t-test comparing diet for each group; ***p < 0.001. (B) Insulin tolerance test and (C) glucose tolerance test conducted after 20 weeks of diet. Statistical differences were assessed by one-way analyses of area under the curve (AUC).