Relationship of Plasma IL-6 on Tumor Size and Growth and Indices of Cachexia
Data is expressed as mean (SEM). A. Plasma IL-6. B. Plasma IL-6 correlated to tumor mass. C. Plasma IL-6 correlated to tumor growth rate. D. Plasma IL-6 correlated to hindlimb muscle mass. Abbreviations: BW: body weight, pg/mL: picograms per milliliter, mg: milligrams, g: grams, PBS: phosphate buffered saline, LLC: Lewis Lung Carcinoma, cm3: centimeters cubed. Plasma IL-6 of 3.9pg/mL is used for undetected values per manufacturer’s instructions. Unpaired t-test was used to compare PBS to LLC (Figures A). * Different than PBS. Pearson Correlation Coefficient was used for correlations (Figure B-D). Statistical significance was set a p<0.05.