Table 1.
Baseline characteristics of patients with bipolar disorder and the reference group.
| All n=35,614 n (%) or Mean (SD) |
Reference Group n=35,326 n (%) or Mean (SD) |
Bipolar Disorder n=288 n (%) or Mean (SD) |
Between-Group Comparison P-value |
|
|---|---|---|---|---|
| Age (years) | 49.8 (13.2) | 49.8 (13.3) | 47.7 (10.9) | .001 |
| Male | 16,435(46.1%) | 16,311 (46.1%) | 124 (43.1%) | .29 |
| European Ancestry | 33,013 (92.7%) | 32,742 (92.7%) | 271 (94.1%) | .014 |
| BMI | 28.03 (6.3) | 28.02 (6.3) | 29.7 (7.8) | .002 |
| HTN History | 6,157 (17.3%) | 6,095 (17.3%) | 62 (21.5%) | <.001 |
| Total Cholesterol | 203.8 (39.2) | 203.8 (39.2) | 207.9 (41.7) | .093 |
| HDL | 53.3 (15.5) | 53.3 (15.4) | 51.6 (16.5) | .034 |
| Current Smoking | 5,453 (15.3%) | 5,361 (15.2%) | 92 (31.9%) | <.001 |
| DM History | 3,648 (10.2%) | 3,606 (10.2%) | 42 (14.6%) | .021 |
| COPD History | 1,637(4.6%) | 1,622(4.6%) | 15 (5.2%) | .084 |
| CKD History | 1,517(4.3%) | 1,502(4.3%) | 15 (5.2%) | .042 |
| Creatinine (mg/dL) | 1.05 (0.42) | 1.05 (0.43) | 1.06 (0.32) | .57 |
| AUD | 1,605 (4.5%) | 1,539 (4.4%) | 66 (22.9%) | <.001 |
| SUD | 569 (1.6%) | 535 (1.5%) | 34 (11.8%) | <.001 |
| Charlson Comorbidity Index | 0.30 (0.85) | 0.30 (0.84) | 0.45 (1.09) | <.001 |
N- Number; SD- Standard Deviation; BMI- Body Mass Index; HTN- Hypertension; HDL- High Density Lipoprotein; DM- Diabetes Mellitus; COPD- Chronic Obstructive Pulmonary Disease; CKD- Chronic Kidney Disease; AUD- Alcohol Use Disorder; SUD- Substance Use Disorder