Table 3.

Associations of overall and disease-free survival with nut consumption among long-term breast cancer survivors

	Overall				Disease-freea
	No. of participants	No. of events	HR (95% CI)b	HR (95% CI)c	No. of participants	No. of events	HR (95% CI)b	HR (95% CI)c
Nuts
No	301	52	1.00 (ref)	1.00 (ref)	285	38	1.00 (ref)	1.00 (ref)
Yes	3148	322	0.90 (0.66, 1.23)	0.90 (0.66, 1.23)	2989	171	0.52 (0.35, 0.75)	0.52 (0.36, 0.76)
≤ Mediand	1573	193	1.00 (0.73, 1.38)	1.00 (0.73, 1.38)	1486	91	0.55 (0.37, 0.81)	0.55 (0.37, 0.82)
> Median	1575	129	0.74 (0.52, 1.05)	0.74 (0.53, 1.06)	1503	80	0.48 (0.31, 0.73)	0.49 (0.32, 0.74)
P trend e			0.022	0.022			0.003	0.004
Peanuts	2501	250	0.85 (0.63, 1.20)	0.87 (0.63, 1.20)	2365	134	0.50 (0.34, 0.74)	0.51 (0.35, 0.75)
Walnuts	2476	221	0.82 (0.59, 1.13)	0.82 (0.59, 1.14)	2361	120	0.46 (0.31, 0.69)	0.47 (0.32, 0.70)
Other nuts	2295	200	0.82 (0.59, 1.14)	0.82 (0.59, 1.14)	2178	118	0.51 (0.34, 0.76)	0.52 (0.35, 0.77)

CI, confidence interval

Models were adjusted for age at diagnosis, total energy intake, income, education, TNM stage, estrogen receptor status, progesterone receptor status, menopause age, physical activity, Chinese Food Pagoda 2007 score, soy food intake, body mass index, and weight change during first 5-year follow-up

^a175 subjects whose events occurred before the dietary assessment were excluded for disease-free analyses; events include breast cancer recurrence, metastasis, and death

^bThe entry time was age at dietary assessment

^cThe entry time was age at breast cancer diagnosis

^dMedian of total nut intake=17.32 g/week

^eP_trend was estimated by treating categories of total nut consumption as ordered values (no-0, ≤median-1, and >median-2).