Table 1.
Demographic data and obstetrical and SARS-CoV-2 infection characteristics
| Case group (n = 14) | Control group (n = 14) | p value | |
|---|---|---|---|
| Demographic maternal data | |||
| Maternal age (SD), years | 31.93 (6.6) | 30.36 (5.8) | 0.506 |
| Maternal weight (SD), kg | 69.32 (10.5) | 68.57 (13.2) | 0.868 |
| Caucasian, % | 9 (64.3) | 4 (28.6) | 0.063 |
| 1° trimester high risk for PE, % | 5 (35.7) | 3 (21.4) | 0.194 |
| Diabetes mellitus, % | 0 (0) | 1 (7.14) | 0.317 |
| Nulliparous, % | 4 (28.6) | 7 (50) | 0.317 |
| Maternal and neonatal outcome at delivery | |||
| Gestational age at birth mean (SD), days | 268.1 (10.8) | 278.9 (7.8) | 0.005 |
| Birth weight, mean (SD), kg | 2,852.5 (467.0) | 3,282.9 (435.9) | 0.018 |
| SGA (<10th percentile), % | 4 (28.6) | 1 (7.2) | 0.146 |
| Induced labor, % | 12 (85.1) | 4 (28.6) | 0.003 |
| Caesarean delivery, % | 5 (35.7) | 0 (0) | 0.015 |
| pH <7.1, % | 2 (14.3) | 0 (0) | 0.541 |
| Pre-term birth (<37 wk gestation), % | 3 (21.4) | 0 (0) | 0.072 |
| Description of SARS-CoV-2 | |||
| Trimester of SARS-CoV-2 infection | |||
| 1°, % | 1 (7.2) | 1 (7.2) | |
| 2°, % | 5 (35.7) | 5 (35.7) | |
| 3°, % | 8 (57.1) | 8 (57.1) | 1 |
| COVID-19 symptoms | |||
| No | 6 (42.9) | 7 (50) | |
| Mild | 6 (42.9) | 7 (50) | |
| Severe | 2 (14.2) | 0 (0) | 0.341 |
| Interval from diagnosis of SARS-CoV-2 to delivery (SD), d | 61.86 (54.79) | 72.64 (57.7) | 0.616 |
| Positive SARS-CoV-2 RT-PCR placenta tissue (CT <37), % | 9 (64.3) | 1 (7.2) | 0.009 |
| Neonatal IgG,* % | 6 (42.9) | 7 (50) | 0.688 |
SD, standard deviation; CT, cycle threshold value RT-PCR; SGA, small for gestational age; PE, preeclampsia.
*Analyzed 24 of 28.