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. 2021 Sep 20:1–6. doi: 10.1159/000519456

Table 2.

Side effects to COVID-19 vaccine reported within 3 days following the first dose

Side effect, n (%) HCW (n = 173) Non-HCW (n = 353) p value
Day 1 after vaccination
 Muscle pain 111 (64) 151 (43) 0.000
 Headache 86 (49.7) 124 (35) 0.002
 Fever 69 (40) 152 (43) 0.511
 Numbness 20 (12) 25 (7) 0.097
 Eye muscle pain 18 (10) 15 (4) 0.012
 Gastrointestinal symptoms 16 (9) 6 (2) 0.000
 Sore throat 14 (8) 8 (2.3) 0.004
 Palpitation 12 (7) 13 (4) 0.126
 Smell/taste loss 4 (3.2) 3 (0.8) 0.225
 Shortness of breath 6 (3.5) 17 (4.8) 0.651
Day 2 after vaccination
 Muscle pain 96 (56) 119 (34) 0.000
 Headache 64 (37) 90 (26) 0.008
 Fever 59 (34) 105 (30) 0.318
 Numbness 15 (9) 12 (3) 0.019
 Eye muscle pain 16 (9) 16 (5) 0.029
 Gastrointestinal symptoms 12 (7) 9 (3) 0.030
 Sore throat 14 (8) 4 (1) 0.000
 Palpitation 11 (6) 9 (3) 0.049
 Smell/taste loss 6 (4) 1 (0.3) 0.006
 Shortness of breath 3 (2) 12 (3) 0.405
Day 3 after vaccination
 Muscle pain 44 (25) 52 (15) 0.004
 Headache 29 (17) 44 (13) 0.182
 Fever 12 (7) 37 (11) 0.205
 Numbness 7 (4) 6 (2) 0.134
 Eye muscle pain 5 (3) 7 (2) 0.541
 Gastrointestinal symptoms 8 (5) 8 (2) 0.176
 Sore throat 11 (6) 0 (0) 0.000
 Palpitation 6 (4) 8 (2) 0.404
 Smell/taste loss 2 (1) 0 (0) 0.108
 Shortness of breath 4 (2) 7 (2) 0.757

HCW, healthcare worker.