Subdistribution hazard ratios for lung cancer mortality as a function of age by CAC score group, smoking status and sex.
Graphed subdistribution hazard ratios (SHR) as a function of age. SHR were adjusted for conventional risk factors for age, sex (except for sex-specific SHR), hypertension, hyperlipidemia, smoking, family history, diabetes. SHR for lung cancer mortality by CAC score groups and sex (A) and by smoking status and sex (B). All SHR are referred to the CAC = 0 group at age 60 years. Lung cancer mortality risk increased exponentially with age and showed the steepest increase for smoking men with CAC ≥ 400. Dotted grey line indicates SHR = 1. CAC = coronary artery calcium score.