Table 1:

Demographic information and injury characteristics at admission for trauma subjects with and without acute traumatic coagulopathy.

	−ATC (n = 32)	+ATC (n = 16)	p-value*
DEMOGRAPHICS
Age (years)	36 (25, 55)	40 (28, 68)	0.47
Male Gender, n (%)	24 (75)	9 (56)	0.19
INJURY CHARACTERISTICS
Blunt Mechanism of Injury, n (%)	9 (28)	9 (56)	0.06
Injury Severity Score	10 (6, 24)	17 (9, 38)	0.07
Severe Head Injury (AIS ≥ 3), n (%)	3 (9)	2 (13)	0.74
aPTT (sec)	26 (24, 27)	29 (25, 35)	0.01
INR	1.1 (1.0, 1.2)	1.3 (1.3, 1.5)	<0.01
Lactate (mmol/L)	3.4 (2.0, 5.5)	5.4 (2.6, 15.3)	0.04
Base Deficit (mmol/L)	2.8 (1.6, 5.1)	8.1 (3.3, 16.9)	<0.01
PREHOSPITAL FLUID ADMINISTRATION
Crystalloids, n (%)	12 (38)	3 (19)	0.19
Blood Product, n (%)	4 (13)	3 (19)	0.56
24-HOUR TRANSFUSION REQUIREMENTS
Packed Red Blood Cells (units)	3 (0, 6)	5 (3, 8)	0.04
Fresh Frozen Plasma (units)	2 (0, 4)	4 (2, 7)	0.12
Platelets (units)†	0 (0, 1)	1 (0, 2)	0.13
Cryoprecipitate (units)	0 (0, 0)	0 (0, 0)	0.34
OUTCOMES
AKI, n (%)	5 (16)	4 (25)	0.43
ALI/ARDS, n (%)	0	0	---
Mechanical Ventilation Duration (days)	2 (0, 4)	3 (1, 13)	0.15
ICU Length of Stay (days)	4 (2, 9)	11 (5, 24)	0.01
Hospital Length of Stay (days)	9 (4, 17)	17 (7, 38)	0.04
Mortality, n (%)	0	0	---

^*Emboldened p-values signify statistically significant comparisons.

^†1 unit of apheresis platelets is equivalent to 4–6 units of whole blood-derived platelet concentrates.

AKI represents acute kidney injury; ALI/ARDS, acute lung injury/acute respiratory distress syndrome; aPTT, activated partial thromboplastin time; ATC, acute traumatic coagulopathy; ICU, intensive care unit; INR, international normalized ratio.