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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Am J Cardiol. 2021 Oct 27;162:80–85. doi: 10.1016/j.amjcard.2021.09.025

Table 6.

Multivariable analysis of predictors of any bleeding

Variable Hazard ratio (95% confidence interval) P-value
Age 1.02 (1.00 – 1.03) 0.007
Female 0.82 (0.67 – 0.99) 0.04
Body mass index 1.00 (0.99 – 1.02) 0.85
Apixaban (reference)
Dabigatran 1.30 (1.03 – 1.63) 0.03
Rivaroxaban 1.49 (1.21 – 1.82) 0.0001
Off-label low dose of DOAC 0.93 (0.72 – 1.21) 0.60
CHA2DS2-VASc score 1.26 (1.18 – 1.34) <.0001
Interacting medication 0.87 (0.71 – 1.05) 0.15
Serum sodium 0.97 (0.95 – 1.00) 0.02
Creatinine clearance 1.00 (1.00 – 1.00) 0.54