Fig 4. Effect of Lingual TrkB inhibition on tumor-induced mechanical sensitivity in the face.

Athymic animals were injected with A. NOK cells and B. HSC2 cells in the tongue and injected with vehicle or 3ug/20ul injection ANA12 in the tongue on day 6,7 and 8 post cell inoculation and von Frey responses were measured at day 9 post cell-inoculation. n=6–10 per group. Data are represented as mean±SEM. Data analyzed with one-way ANOVA with Bonferroni post hoc test at p<0.05.