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Elevation of cytokines and molecules involved in T-cell function in CVIDc. A, Plasma cytokines by Olink in uncomplicated CVID, CVIDc, XLA, HIgM, IgAD, and HCs. B, Plasma IL-12, IFN-γ, and TNF by Luminex, IL-6 by ELISA. XLA (purple diamonds), HIgM (teal diamonds), IgAD (orange diamonds). HIgM, Hyper-IgM syndrome; IgAD, selective IgA deficiency; XLA, X-linked agammaglobulinemia. **P < .01, ***P < .001, **** P < .0001.
