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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2021 Jun 17;149(1):315–326.e9. doi: 10.1016/j.jaci.2021.06.008

FIG 2.

FIG 2.

Cytokine and sCD14 elevation corresponds with greater antibody defect in CVID. A, Plasma sCD14. XLA (purple diamonds), HIgM (teal diamonds), IgAD (orange diamonds). B, Serum IgA. C, IgA and sCD14 correlation. D, Plasma LPS-specific IgA. E, LPS-specific IgA and sCD14 correlation. F, Plasma LPS-specific IgM. G, LPS-specific IgM and sCD14 correlation. H, LPS-specific IgA and IL-12 correlation. I, LPS-specific IgM and IL-12 correlation. J, Isotype-switched memory B cells and IL-12 correlation. HIgM, Hyper-IgM syndrome; IgAD, selective IgA deficiency; XLA, X-linked agammaglobulinemia. Red triangles denote CVIDc, and blue triangles denote uncomplicated CVID. *P < .05, **P < .01, ***P < .001, ****P < .0001.