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. 2021 Dec 3;9:767006. doi: 10.3389/fcell.2021.767006

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Copyright © 2021 Wang, Li, Li, Li, Gao, Bao, Wang, Liu, Xue and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decreased adipogenic differentiation accompanied by increased TAZ expression was also mediated by p-ERK/ERK signaling after CCG treatment. (A–C) Relative mRNA and protein levels of TAZ to GAPDH at Day 3 after the treatment during adipogenesis. (D–F) Relative mRNA and protein levels of p-ERK at Day 3 after the treatment during adipogenesis. (G, H) Representative images of Oil Red O staining showed the lipid droplets were lessened by CCG. Scale bar: 100 μm (n = 3) *p < 0.05 vs. the control group (cells cultured in adipogenic medium during adipogenesis); #p < 0.05 vs. the CCG treatment group.