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. 2021 Dec 3;9:767006. doi: 10.3389/fcell.2021.767006

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Copyright © 2021 Wang, Li, Li, Li, Gao, Bao, Wang, Liu, Xue and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Curculigoside ameliorates bone loss by influencing mesenchymal stem cell fate in aging mice. CCG ameliorated age-related bone loss by upregulating TAZ expression to induce switch from adipogenesis to osteogenesis of BMSCs in aging mice through MEK/ERK-TAZ axis.