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. 2021 Dec 3;14:742790. doi: 10.3389/fnmol.2021.742790

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Copyright © 2021 Montalbano, Jaworski, Garcia, Ellsworth, McAllen, Routh and Kayed.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tau-dependent Gene expression. (A) Schematic representation of experimental plan, from Tet induction in WT and P301L Tau iHEK to RNA isolation, sequencing to gene expression analysis. (B) Volcano Plot for Down- and Up-regulated gene in WT tau iHEK. (C) Volcano Plot for Down- and Up-regulated gene in P301L tau iHEK. (D) Gene Lists of Down-Regulated (Red Boxes) and Up-Regulated (Green Boxes) Genes in WT tau iHEK. (E) Gene Lists of Down-Regulated (Red Boxes) and Up-Regulated (Green Boxes) Genes in P301L tau iHEK.