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. 2021 Dec 3;15:787362. doi: 10.3389/fnbeh.2021.787362

FIGURE 4.

FIGURE 4

Effect of NAcc Shell PAC1R shRNA knockdown on saccharin self-administration (FR-1 schedule) (n = 7–8/group). (A,B) Rats with NAcc Shell PAC1R shRNA knockdown (“AAV-PAC1R KD”) and control rats (“AAV-CTRL”) showed no significant differences in self-administration of the alternative reinforcer saccharin, or of the concurrently available water (C,D). Data represent Mean ± SEM.