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. 2021 Dec 3;12:760249. doi: 10.3389/fimmu.2021.760249

Table 2.

Demographics, clinical and laboratory parameters in hemodialysis patients and kidney transplant recipients presented as responders versus non responders in each group after the second dose of vaccine.

Hemodialysis patients (n = 34) p Kidney Transplant Recipients (n = 54) p
Responders (n= 31) Non-Responders (n=3) Responders (n=16) Non-Responders (n=38)
Age, yr 69.2 ± 12 71.3 ± 17.6 0.78 55.01 ± 2.23 59.5 ± 7.48 0.18
Male sex 22, 71.0% 1, 33.3% 0.24 13, 81.3% 25, 65.8% 0.26
BMI, kg/m2 25.23 ± 4.19 23.77 ± 2.86 0.56 25.85 ± 3.99 25.98 ± 4.05 0.92
Diabetes mellitus 7, 22.6% 2, 66.7% 0.16 3, 18.7% 7, 18.4% 0.98
History of Cancer 1, 6.7% 1, 6.2% 4, 10.5% 0.62
Time on dialysis, years 5.81 ± 4.88 4.66 ± 1.53 0.69
Time from Transplant, years 12.94 ± 9.62 11.45 ± 7.70 0.55
Donor type
Deceased 9, 56.2% 26, 68.4% 0.55
Live 7, 43.8% 11, 28.9%
Both 1, 2.6%
ABO group 0.57 0.27
A 10, 32.2% 2, 66.7% 4, 25.0% 17, 47.2%
AB 2, 6.5% 2, 5.6%
B 8, 25.8% 1, 33.3% 2, 12.5% 5, 13.9%
O 11, 35.5% 10, 62.5% 12, 33.3%
Hb, g/dl 10.97 ± 1.00 9.37 ± 1.01 0.013 14.11 ± 1.85 13.30 ± 1.88 0.15
WBC, 103/ml 8326 ± 10050 6496 ± 4010 0.76 7961 ± 2751 8277 ± 2663 0.69
Tacrolimus 10, 62.5% 31, 81.6% 0.13
Cyclosporine 6, 37.5% 7, 18.4% 0.13
MMF/MPA 12, 75.0% 38, 100.0% 0.006
Steroids 12, 75.0% 34, 89.5% 0.17
Tacrolimus+MMF/MPA 8, 50.0% 31, 81.6% 0.018
Tacrolimus+MMF/MPA+Steroids 7, 43.8% 28, 73.7% 0.035
Tacrolimus levels, ng/ml 6.2 ± 1.7 6.8 ± 1.2 0.24
Cyclosporine T0 levels, ng/ml 102.6 ± 19.2 104.5 ± 26.0 0.88
eGFR, ml/min per 1.73m2 61.6 ± 15.4 48.9 ± 17.2 0.014
Urine Protein, mg/24h 307 ± 550 339 ± 345 0.80

BMI, body mass index; CNI, calcineurin inhibitor; eGFR, estimated glomerular filtration rate; MMF, mycophenolate mofetil; MPA, mycophenolic acid.