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. 2021 Dec 15;17(1):70–86. doi: 10.1515/med-2021-0408

Table 3.

Result of meta-analysis for calculation of lipid profile SMD; publication bias and fill and trim method

Lipids profile Meta-analysis Egger’s test for publication bias Fill and trim
Number I2% SMD Coefficient (95% CI) P-value SMD 95% CI
TC 32 93.7 0.23 (0.11–0.34) 1.24 (−0.60–3.10) 0.179
LDL 29 96.2 0.14 (−0.04 to 0.32)* −0.05 (−2.75–2.66) 0.972
HDL 29 94.6 −0.35 (−0.54 to −0.16) −1.77 (−4.37–0.08) 0.173
TG 32 98.6 1.14 (0.91–1.38) 5.21 (1.70–8.71) 0.005 1.13 (0.92–1.39)
VLDL 31 98.2 0.99 (0.71–1.27) 2.04 (−2.23–6.31) 0.337
TG/HDL ratio 11 95.4 0.65 (0.36–0.94) 3.58 (−1.29–8.46) 0.130

*No significance; SMD: standardized mean difference; TC: total cholesterol; TG: triglyceride; CI: confidence interval; LDL: low-density lipoproteins; HDL: high-density lipoproteins; VLDL: very low-density lipoproteins.