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. 2021 Dec 3;9:764125. doi: 10.3389/fcell.2021.764125

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Copyright © 2021 Chu, Shan, Ji, Wang and Niu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exploring the clinical practice value of TMSig. (A) Kaplan-Meier curves for overall survival (OS) of patients from the train cohort. (B) Kaplan-Meier curves for OS of patients from the test cohort. (C) Kaplan-Meier curves for OS of patients from the IMvigor210 cohort. (D) Independent prognostic analysis of TMSig. (E) Kaplan-Meier curves for OS of patients from the GSE32548 cohort. (F) Kaplan-Meier curves for OS of patients from the GSE48075 cohort. (G) Kaplan-Meier curves for OS of patients from the UTUC cohort. (H) Dynamic nomogram for clinical practice. (I) Calibration curve analysis. (J) The decision curves analysis. (K) The c-index of TMSig compared with other signatures.