Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 3;9:764125. doi: 10.3389/fcell.2021.764125

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Chu, Shan, Ji, Wang and Niu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Molecular differences between high- and low-score subgroups and distribution among previous subtypes. (A) The TMSig score in the high score group was significantly higher than that in the low score group. (B) The expression level of immune checkpoints in the high score and low score groups. (C) Immune infiltration cells are expressed in the high score and low score groups (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). (D) The immune therapy response and TIDE value of patients with urothelial cancer. (E) The subclass mapping analysis showed a significant difference in response to anti-PD-1 therapy among these two groups. The distribution of TMSig score of the IMvigor210 cohort in molecular subtypes. (F) Baylor subtype, (G) UNC subtype, (H) MDA subtype, (I) TCGA subtypes. The distribution of TMSig score of the TCGA cohort in molecular subtypes. (J) Baylor subtype, (K) UNC subtype, (L) MDA subtype, (M) TCGA subtypes.