Table 7.
Diagnostic Accuracy of FIB-4 and NFS for Advanced Fibrosis (A) and Collagen Proportionate Area (B) >7.6%
| Cutoff | Sensitivity | Specificity | PPV | NPV | LR+ | LR− | |
|---|---|---|---|---|---|---|---|
| A | |||||||
| FIB-4 | 1.3 | 0.72 | 0.43 | 0.46 | 0.80 | 1.26 | 0.66 |
| NFS | −1.455 | 0.84 | 0.36 | 0.40 | 0.82 | 1.32 | 0.43 |
| B | |||||||
| FIB-4 | 1.3 | 0.93 | 0.44 | 0.24 | 0.98 | 1.65 | 0.16 |
| NFS | −1.455 | 0.93 | 0.35 | 0.18 | 0.97 | 1.44 | 0.20 |
Abbreviations: LR+, positive likelihood ratio; LR−, negative likelihood ratio; NFS, NAFLD Fibrosis Score; NPV, negative-predictive value; PPV, positive-predictive value.