Study‐ID | Setting | Condition | Indication | Scale | Drug | Daily dose | Duration, weeks | Number randomised |
Allain 2000 | Nursing home or hospitalised | AD, VD, mixed type | Agitation | MOSESa | Tiapride | Up to 300 mg | 3 | 306 |
Ballard 2005 | Care facilities | AD | Agitation | CMAI | Quetiapine | 50 mg to 100 mg | 6 | 62 |
Zhong 2007 | Nursing homes, assisted‐living facilities | AD, VD | Agitation | PANSS‐EC | Quetiapine | 100 mg or 200 mg | 10 | 333 |
Schneider 2006 CATIE‐AD | Community‐dwelling or assisted‐living facilities | AD | Agitation | NPI agitationb | Olanzapine, Quetiapine or Risperidone | Flexible dosec | 12 | 421 |
Brodaty 2003 RIS‐AUS‐05 | Nursing homes | AD, VD, mixed type | Agitation | CMAI aggressionb | Risperidone | up to 2 mg | 12 | 345 |
Grossberg 2020a | Community‐dwelling or care facility | AD | Agitation | CMAI | Brexpiprazole | 0.5 mg, 1 mg and 2 mg | 12 | 433 |
Grossberg 2020b | Community‐dwelling or care facility | AD | Agitation | CMAI | Brexpiprazole | 0.5 mg to 2 mg | 12 | 270 |
Japic CTI 142578 2015 | Hospital or care facilities | AD | Agitation | Not reported | Aripiprazole | 2, 3 mg or 6 mg | 10 | 150 |
Tariot 2006 | Nursing homes | AD | Psychosis | NPI‐NH psychosisb | Quetiapine | 25 mg to 600 mg | 10 | 284 |
Paleacu 2008 | Not reported | AD | Psychosis | NPI‐NH psychosisb | Quetiapine | 50 mg to 300 mg | 6 | 40 |
Ballard 2018 | Nursing homes | AD | Psychosis | NPI‐NH psychosisb | Pimavanserin | 34 mg | 12 | 181 |
De Deyn 2004 F1D MC HGIV | Nursing homes, continuing‐care hospitals | AD | Psychosis | NPI‐NH psychosisb | Olanzapine | 1 mg, 2.5 mg, 5 mg or 7.5 mg | 10 | 652 |
Deberdt 2005 F1D MC HGGU | Outpatients, nursing homes, assisted‐living centres | AD, VD, mixed type | Psychosis | NPI(‐NH) psychosisb | Olanzapine or Risperidone |
2.5 mg to 10 mg, respectively 0.5 mg to 2 mg |
10 | 494 |
Mintzer 2006 RIS USA 232 | Nursing homes, long‐term care | AD, VD | Psychosis | BEHAVE‐AD psychosisb | Risperidone | 1 mg to 1.5 mg | 8 | 473 |
NCT00287742 2006 | In‐ or outpatients | AD | Psychosis | BEHAVE‐AD psychosisb | Risperidone | 0.5 mg to ‐2 mg | 8 | 33 |
RIS‐INT‐83 2003 | Nursing homes or long‐term care | AD | Psychosis | BEHAVE‐AD | Risperidone | 1 mg to 1.5 mg | 8 | 18 |
Schneider 2003 RIS USA 63 | Nursing homes, hospital | AD, VD, mixed type | Psychosis | BEHAVE‐AD psychosisb | Risperidone | 1 mg, 2 mg or 3 mg | 12 | 463 (psychosis subgroup) |
Streim 2008 | Institutionalised subjects | AD, VD | Psychosis | NPI‐NH psychosisb | Aripiprazole | 2 mg to 15 mg | 10 | 256 |
Mintzer 2007 | Nursing homes, assisted‐living facilities | AD | Psychosis | NPI‐NH psychosisb | Aripiprazole | 2, 5 mg or 10 mg | 10 | 487 |
De Deyn 2005 | Community‐dwelling | AD | Psychosis | NPI Psychosisb | Aripiprazole | 2 mg to 15 mg | 10 | 208 |