TABLE 3.
Effect of vehicle or cisplatin (30 mg/kg, intraperitoneal) on the body weight and food and water intake of Suncus murinus.
| Body weight (g) | Food Intake (g·kg−1) | Water Intake (ml·kg−1) | ||||
|---|---|---|---|---|---|---|
| Vehicle | Cisplatin | Vehicle | Cisplatin | Vehicle | Cisplatin | |
| -24–0 h | 70.1 ± 1.6 | 69.1 ± 1.7 | 95.2 ± 4.8 | 102.1 ± 9.5 | 199.6 ± 14.1 | 223.7 ± 3.3 |
| 0–24 h | 69.9 ± 1.7 | 64.5 ± 1.9 | 94.9 ± 7.0 | 48.7 ± 10.0***### | 203.2 ± 16.0 | 96.0 ± 7.7***### |
| 24–48 h | 69.9 ± 2.4 | 63.3 ± 1.7 | 92.1 ± 6.6 | 59.0 ± 7.8*## | 180.5 ± 11.2 | 126.3 ± 17.4### |
| 48–72 h | 70.8 ± 2.2 | 59.2 ± 2.0***## | 101.4 ± 4.6 | 30.2 ± 13.8***### | 184.5 ± 16.2 | 105.0 ± 17.8***### |
Data are means ± standard errors of the mean for 7 – 8 animals. Significant differences relative to the baseline (-24–0 h) for each group are shown as ## p < 0.01 or ### p < 0.001; Significant differences between cisplatin and vehicle groups are shown as * p < 0.05, ** p < 0.01 or *** p < 0.001 (two-way analysis of variance, followed by Bonferroni tests).