Table 3.

Diagnostic Test Characteristics for US-Born PLWH Estimated Directly From Latent Class Analysis Using Standard US Cutoffs at 4.7% Estimated LTBI Prevalence

	Sensitivity (95% Crl)	Specificity (95% Crl)	PPV (95% Crl)	NPV (95% CrI)
TST (≥5 mm)	54.2% (45.2–64.3)	96.8% (95.7–97.7)	45.4% (33.3–58.4)	97.7% (96.4–98.7)
QFT (≥0.35 IU/mL)	72.2% (58.7–85.4)	96.5% (95.3–97.6)	50.7% (37.1–65.6)	98.6% (97.4–99.4)
TSPOT (≥8 spots)	51.9% (39.3–66.7)	99.7% (99.3–99.9)	90.0% (77.1–98.1)	97.6% (96.1–98.8)

Abbreviations: Crl, credible interval; LTBI, latent tuberculosis infection; NPV, negative predictive value; PLWH, people living with human immunodeficiency virus; PPV, positive predictive value; QFT, QuantiFERON Gold In-Tube; TSPOT, T-SPOT.TB; TST, tuberculin skin test.