Table 4.

Differences in Diagnostic Test Characteristics for US-Born PLWH Estimated Directly From Latent Class Analysis Using Standard US Cutoffs at 4.7% Estimated LTBI Prevalence

Test Combination	Difference (95% CrI)
Sensitivity:
TST vs QFT	−18.0% (−31.8 to −4.1)
TST vs TSPOT	2.2% (−11.5 to 15.2)
QFT vs TSPOT	20.2% (5.2 to 35.3)
Specificity:
TST vs QFT	0.2% (−1.2 to 1.7)
TST vs TSPOT	−3.0% (−4.1 to −2.0)
QFT vs TSPOT	−3.2% (−4.5 to −2.0)
PPV:
TST vs QFT	−5.3% (−18.8 to 7.8)
TST vs TSPOT	−44.5% (−58.5 to −29.1)
QFT vs TSPOT	−39.3% (−54.5 to −22.4)
NPV:
TST vs QFT	−0.9% (−1.7 to −.2)
TST vs TSPOT	0.1% (−.6 to .7)
QFT vs TSPOT	0.9% (.2 to 1.9%)

Bold font indicates a statistically significant mean difference.

Abbreviations: Crl, credible interval; LTBI, latent tuberculosis infection; NPV, negative predictive value; PLWH, people living with human immunodeficiency virus; PPV, positive predictive value; QFT, QuantiFERON Gold In-Tube; TSPOT, T-SPOT.TB; TST, tuberculin skin test.