Table 3.
Comparison of the clinical outcomes in the POSEIDON groups.
| POSEIDON group 1 (n = 151) | POSEIDON group 2 (n = 101) | POSEIDON group 3 (n = 71) | POSEIDON group 4 (n = 105) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GH | Non-GH | p-value | GH | Non-GH | p-value | GH | Non-GH | p-value | GH | Non-GH | p-value | |
| No. of oocytes retrieved | 8.62 ± 4.30 | 5.62 ± 2.40 | <0.001* | 6.86 ± 3.52 | 5.29 ± 2.04 | <0.001* | 5.27 ± 2.98 | 4.45 ± 2.37 | 0.025* | 4.14 ± 2.95 | 3.73 ± 2.45 | 0.213 |
| No. of two pronuclei | 5.30 ± 3.08 | 3.22 ± 1.77 | <0.001* | 4.47 ± 2.84 | 3.43 ± 1.85 | 0.001* | 3.28 ± 2.45 | 2.77 ± 1.88 | 0.057 | 2.63 ± 2.22 | 2.63 ± 1.76 | 1.000 |
| No. of day-3 good-quality embryos | 2.31 ± 2.22 | 1.13 ± 1.28 | <0.001* | 2.61 ± 2.23 | 1.76 ± 1.52 | <0.001* | 1.63 ± 1.65 | 0.96 ± 1.22 | 0.002* | 1.25 ± 1.39 | 1.16 ± 1.11 | 0.594 |
| No. of embryos available to transfer | 2.54 ± 1.87 | 1.15 ± 0.91 | <0.001* | 2.12 ± 1.63 | 1.44 ± 1.14 | <0.001* | 1.86 ± 1.53 | 0.94 ± 0.97 | <0.001* | 1.32 ± 1.16 | 0.96 ± 0.90 | 0.004* |
| Stage of embryo transferred | 0.507 | 0.797 | 0.192 | 0.334 | ||||||||
| Cleavage-stage embryo | 85 (79.44) | 71 (75.53) | 48 (80.00) | 39 (78.00) | 39 (88.64) | 24 (77.42) | 42 (77.78) | 34 (69.39) | ||||
| Blastocyst | 22 (20.56) | 23 (24.47) | 12 (20.00) | 11 (22.00) | 5 (11.36) | 7 (22.58) | 12 (22.22) | 15 (30.61) | ||||
| No. of embryos transferred | 0.044* | 0.801 | 0.407 | 0.096 | ||||||||
| One embryo transferred | 32 (29.91) | 41 (43.62) | 23 (38.33) | 18 (36.00) | 13 (29.55) | 12 (38.71) | 22 (40.74) | 28 (57.14) | ||||
| Two embryos transferred | 75 (70.09) | 53 (56.38) | 37 (61.67) | 32 (64.00) | 31 (70.45) | 19 (61.29) | 32 (59.26) | 21 (42.86) | ||||
| Chemical pregnancy rate/ET | 62/107 (57.94) | 25/94 (26.60) | <0.001* | 27/60 (45.00) | 14/50 (28.00) | 0.066 | 25/44 (56.82) | 6/31 (19.35) | 0.001* | 25/54 (46.30) | 6/49 (12.24) | <0.001* |
| Clinical pregnancy rate/ET | 58/107 (54.21) | 7/94 (7.45) | <0.001* | 21/60 (35.00) | 5/50 (10.00) | 0.002* | 21/44 (47.73) | 3/31 (9.68) | 0.001* | 20/54 (37.04) | 2/49 (4.08) | <0.001* |
| Clinical pregnancy loss rate/CP | 7/58 (12.07) | 7/7 (100.00) | <0.001* | 4/21 (19.05) | 5/5 (100.00) | 0.002* | 1/21 (4.76) | 3/3 (100.00) | 0.002* | 7/20 (35.00) | 2/2 (100.00) | 0.049* |
| Live birth rate/ET | 51/107 (47.66) | 0 | <0.001* | 17/60 (28.33) | 0 | <0.001* | 20/44 (45.45) | 0 | <0.001* | 13/54 (24.07) | 0 | <0.001* |
All values presented as mean ± SD or n (%).
GH, growth hormone; ET, embryo transfer; CP, clinical pregnancy.
In bold: The values associated with GH.
*indicates statistical significances of p < 0.05.