Table 4.
GEE regression analysis for the number of oocytes retrieved.
Independent variable | POSEIDON group 1 | POSEIDON group 2 | POSEIDON group 3 | POSEIDON group 4 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value | |
GH supplementation | ||||||||||||
Non-GH | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GH | 1.47 | 1.36–1.59 | <0.001* | 1.31 | 1.15–1.49 | <0.001* | 1.17 | 1.00–1.36 | 0.054 | 1.04 | 0.89–1.20 | 0.637 |
Age | 1.00 | 0.99–1.02 | 0.624 | 1.00 | 0.98–1.02 | 0.838 | 1.01 | 0.98–1.05 | 0.355 | 1.00 | 0.98–1.03 | 0.885 |
BMI | 0.98 | 0.97–1.00 | 0.033* | 0.99 | 0.97–1.01 | 0.231 | 1.01 | 0.99–1.01 | 0.458 | 1.00 | 0.97–1.02 | 0.766 |
AMH | 1.04 | 1.02–1.07 | 0.001* | 0.96 | 0.92–1.00 | 0.062 | 1.68 | 1.24–2.28 | 0.001* | 1.60 | 1.24–2.05 | <0.001* |
FSH | 0.99 | 0.96–1.03 | 0.741 | 0.95 | 0.92–0.99 | 0.005* | 0.98 | 0.95–1.01 | 0.124 | 0.97 | 0.95–0.99 | 0.013* |
AFC | 1.01 | 1.00–1.02 | 0.075 | 1.03 | 1.01–1.05 | 0.001* | 1.02 | 0.98–1.06 | 0.352 | 1.01 | 0.98–1.05 | 0.381 |
COH protocol | ||||||||||||
GnRH antagonist | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GnRH agonist long | 1.20 | 1.08–1.32 | <0.001* | 1.14 | 0.97–1.33 | 0.114 | 1.12 | 0.92–1.37 | 0.261 | 1.31 | 1.06–1.62 | 0.012* |
GnRH agonist ultra-long | 1.05 | 0.91–1.22 | 0.490 | 1.31 | 1.06–1.62 | 0.014* | 0.84 | 0.64–1.10 | 0.209 | 1.16 | 0.89–1.51 | 0.268 |
GnRH agonist short | 1.09 | 0.96–1.24 | 0.190 | 1.23 | 1.05–1.45 | 0.010* | 0.91 | 0.75–1.11 | 0.353 | 1.09 | 0.91–1.29 | 0.355 |
Duration of Gn | 1.00 | 0.97–1.02 | 0.740 | 1.02 | 0.98–1.07 | 0.292 | 1.05 | 1.00–1.10 | 0.033* | 1.04 | 0.99–1.09 | 0.121 |
Gn dose (per 100 IU) | 1.01 | 1.00–1.01 | 0.006* | 1.00 | 0.99–1.01 | 0.777 | 1.00 | 0.99–1.01 | 0.735 | 1.00 | 1.00–1.00 | 0.574 |
GH, growth hormone; BMI, body mass index; AMH, anti-Müllerian hormone; FSH, follicle-stimulating hormone; AFC, antral follicle count; COH, controlled ovarian hyperstimulation; GnRH, gonadotropin-releasing hormone; Gn, gonadotropin.
In bold: The values associated with GH.
*indicates statistical significances of p < 0.05.