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. 2021 Dec 2;12:790160. doi: 10.3389/fendo.2021.790160

Table 4.

GEE regression analysis for the number of oocytes retrieved.

Independent variable POSEIDON group 1 POSEIDON group 2 POSEIDON group 3 POSEIDON group 4
IRR 95% CI p-value IRR 95% CI p-value IRR 95% CI p-value IRR 95% CI p-value
GH supplementation
Non-GH _ _ _ _ _ _ _ _
GH 1.47 1.36–1.59 <0.001* 1.31 1.15–1.49 <0.001* 1.17 1.00–1.36 0.054 1.04 0.89–1.20 0.637
Age 1.00 0.99–1.02 0.624 1.00 0.98–1.02 0.838 1.01 0.98–1.05 0.355 1.00 0.98–1.03 0.885
BMI 0.98 0.97–1.00 0.033* 0.99 0.97–1.01 0.231 1.01 0.99–1.01 0.458 1.00 0.97–1.02 0.766
AMH 1.04 1.02–1.07 0.001* 0.96 0.92–1.00 0.062 1.68 1.24–2.28 0.001* 1.60 1.24–2.05 <0.001*
FSH 0.99 0.96–1.03 0.741 0.95 0.92–0.99 0.005* 0.98 0.95–1.01 0.124 0.97 0.95–0.99 0.013*
AFC 1.01 1.00–1.02 0.075 1.03 1.01–1.05 0.001* 1.02 0.98–1.06 0.352 1.01 0.98–1.05 0.381
COH protocol
 GnRH antagonist _ _ _ _ _ _ _ _
 GnRH agonist long 1.20 1.08–1.32 <0.001* 1.14 0.97–1.33 0.114 1.12 0.92–1.37 0.261 1.31 1.06–1.62 0.012*
 GnRH agonist ultra-long 1.05 0.91–1.22 0.490 1.31 1.06–1.62 0.014* 0.84 0.64–1.10 0.209 1.16 0.89–1.51 0.268
 GnRH agonist short 1.09 0.96–1.24 0.190 1.23 1.05–1.45 0.010* 0.91 0.75–1.11 0.353 1.09 0.91–1.29 0.355
Duration of Gn 1.00 0.97–1.02 0.740 1.02 0.98–1.07 0.292 1.05 1.00–1.10 0.033* 1.04 0.99–1.09 0.121
Gn dose (per 100 IU) 1.01 1.00–1.01 0.006* 1.00 0.99–1.01 0.777 1.00 0.99–1.01 0.735 1.00 1.00–1.00 0.574

GH, growth hormone; BMI, body mass index; AMH, anti-Müllerian hormone; FSH, follicle-stimulating hormone; AFC, antral follicle count; COH, controlled ovarian hyperstimulation; GnRH, gonadotropin-releasing hormone; Gn, gonadotropin.

In bold: The values associated with GH.

*indicates statistical significances of p < 0.05.