Table 5.
Independent variable | POSEIDON group 1 | POSEIDON group 2 | POSEIDON group 3 | POSEIDON group 4 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value | |
GH supplementation | ||||||||||||
Non-GH | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GH | 2.13 | 1.78–2.56 | <0.001* | 1.54 | 1.26–1.89 | <0.001* | 1.47 | 1.10–1.98 | 0.010* | 1.00 | 0.78–1.30 | 0.971 |
Age | 1.02 | 0.98–1.06 | 0.271 | 1.02 | 0.98–1.06 | 0.356 | 1.00 | 0.94–1.06 | 0.890 | 0.98 | 0.93–1.03 | 0.354 |
BMI | 0.98 | 0.95–1.00 | 0.093 | 0.96 | 0.93–1.00 | 0.042* | 1.02 | 0.97–1.08 | 0.377 | 0.99 | 0.94–1.05 | 0.845 |
AMH | 1.06 | 1.01–1.11 | 0.014* | 0.92 | 0.84–1.00 | 0.043* | 2.02 | 1.07–3.83 | 0.030* | 0.88 | 0.55–1.39 | 0.573 |
FSH | 0.96 | 0.91–1.02 | 0.222 | 0.94 | 0.89–0.99 | 0.031* | 1.03 | 0.98–1.09 | 0.237 | 0.99 | 0.95–1.04 | 0.756 |
AFC | 0.99 | 0.97–1.01 | 0.379 | 1.04 | 1.01–1.07 | 0.012* | 1.04 | 0.97–1.13 | 0.270 | 0.99 | 0.93–1.06 | 0.792 |
COH protocol | ||||||||||||
GnRH antagonist | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GnRH agonist long | 1.25 | 1.01–1.55 | 0.037* | 1.24 | 0.96–1.60 | 0.099 | 1.35 | 0.94–1.96 | 0.108 | 1.74 | 1.20–2.52 | 0.004* |
GnRH agonist ultra-long | 0.57 | 0.39–0.83 | 0.003* | 1.05 | 0.73–1.52 | 0.784 | 1.28 | 0.80–2.05 | 0.311 | 1.53 | 0.95–2.46 | 0.081 |
GnRH agonist short | 1.31 | 1.01–1.70 | 0.038* | 1.33 | 1.02–1.74 | 0.038* | 0.76 | 0.51–1.13 | 0.178 | 1.09 | 0.80–1.48 | 0.600 |
Duration of Gn | 0.99 | 0.93–1.04 | 0.628 | 1.05 | 0.98–1.13 | 0.158 | 1.02 | 0.93–1.12 | 0.642 | 1.07 | 0.98–1.17 | 0.144 |
Gn dose (per 100 IU) | 1.01 | 0.99–1.02 | 0.272 | 1.00 | 0.99–1.01 | 0.994 | 0.99 | 0.97–1.01 | 0.219 | 1.00 | 1.00–1.00 | 0.024* |
GH, growth hormone; BMI, body mass index; AMH, anti-Müllerian hormone; FSH, follicle-stimulating hormone; AFC, antral follicle count; COH, controlled ovarian hyperstimulation; GnRH, gonadotropin-releasing hormone; Gn, gonadotropin.
In bold: The values associated with GH.
*indicates statistical significances of p < 0.05.