Table 6.
Independent variable | POSEIDON group 1 | POSEIDON group 2 | POSEIDON group 3 | POSEIDON group 4 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value | |
GH supplementation | ||||||||||||
Non-GH | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GH | 2.33 | 1.96–2.77 | <0.001* | 1.57 | 1.26–1.95 | <0.001* | 2.06 | 1.51–2.82 | <0.001* | 1.31 | 1.02–1.69 | 0.033* |
Age | 1.00 | 0.96–1.04 | 0.993 | 0.98 | 0.94–1.02 | 0.369 | 1.02 | 0.96–1.08 | 0.539 | 0.99 | 0.95–1.04 | 0.796 |
BMI | 0.98 | 0.95–1.01 | 0.173 | 0.97 | 0.93–1.01 | 0.135 | 1.05 | 1.00–1.10 | 0.037* | 0.98 | 0.93–1.04 | 0.500 |
AMH | 1.06 | 1.01–1.11 | 0.011* | 0.94 | 0.86–1.03 | 0.213 | 2.29 | 1.27–4.13 | 0.006* | 0.97 | 0.59–1.59 | 0.899 |
FSH | 1.01 | 0.95–1.07 | 0.771 | 0.95 | 0.89–1.02 | 0.157 | 0.99 | 0.93–1.04 | 0.599 | 0.99 | 0.95–1.03 | 0.661 |
AFC | 0.98 | 0.96–1.00 | 0.118 | 1.02 | 0.99–1.06 | 0.178 | 1.01 | 0.94–1.08 | 0.806 | 1.02 | 0.95–1.08 | 0.654 |
COH protocol | ||||||||||||
GnRH antagonist | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GnRH agonist long | 1.15 | 0.94–1.41 | 0.166 | 1.23 | 0.94–1.61 | 0.130 | 1.01 | 0.69–1.48 | 0.955 | 1.46 | 1.02–2.11 | 0.041* |
GnRH agonist ultra-long | 0.91 | 0.66–1.24 | 0.551 | 1.01 | 0.67–1.51 | 0.971 | 0.88 | 0.55–1.41 | 0.597 | 1.30 | 0.82–2.07 | 0.260 |
GnRH agonist short | 1.24 | 0.97–1.60 | 0.090 | 1.18 | 0.88–1.58 | 0.261 | 0.95 | 0.64–1.40 | 0.799 | 1.02 | 0.75–1.39 | 0.915 |
Duration of Gn | 1.04 | 0.98–1.10 | 0.169 | 1.05 | 0.97–1.13 | 0.235 | 1.08 | 0.98–1.17 | 0.108 | 1.05 | 0.96–1.15 | 0.284 |
Gn dose (per 100 IU) | 0.99 | 0.98–1.00 | 0.150 | 0.99 | 0.97–1.00 | 0.130 | 0.99 | 0.97–1.00 | 0.139 | 1.00 | 1.00–1.00 | 0.083 |
GH, growth hormone; BMI, body mass index; AMH, anti-Müllerian hormone; FSH, follicle-stimulating hormone; AFC, antral follicle count; COH, controlled ovarian hyperstimulation; GnRH, gonadotropin-releasing hormone; Gn, gonadotropin.
In bold: The values associated with GH.
*indicates statistical significances of p < 0.05.