Table 7.
Independent variable | POSEIDON group 1 | POSEIDON group 2 | POSEIDON group 3 | POSEIDON group 4 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
GH supplementation | ||||||||||||
Non-GH | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GH | 4.18 | 2.26–7.73 | <0.001* | 1.66 | 0.56–4.94 | 0.361 | 8.11 | 2.54–25.95 | <0.001* | 5.91 | 1.87–18.73 | 0.003* |
Age | 0.93 | 0.81–1.07 | 0.284 | 0.95 | 0.83–1.09 | 0.437 | 1.08 | 0.86–1.35 | 0.506 | 1.05 | 0.89–1.23 | 0.549 |
BMI | 0.99 | 0.89–1.10 | 0.843 | 1.02 | 0.90–1.17 | 0.713 | 1.23 | 1.01–1.50 | 0.043* | 1.03 | 0.84–1.25 | 0.796 |
AMH | 1.12 | 0.93–1.35 | 0.248 | 0.94 | 0.74–1.19 | 0.610 | 4.00 | 0.35–45.09 | 0.262 | 0.54 | 0.09–3.44 | 0.517 |
FSH | 0.92 | 0.75–1.13 | 0.430 | 1.10 | 0.90–1.36 | 0.350 | 0.93 | 0.72–1.19 | 0.545 | 0.79 | 0.63–1.00 | 0.048* |
AFC | 0.91 | 0.84–1.00 | 0.049* | 1.16 | 1.04–1.30 | 0.010* | 1.07 | 0.82–1.39 | 0.616 | 1.08 | 0.86–1.35 | 0.514 |
COH protocol | ||||||||||||
GnRH antagonist | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GnRH agonist long | 1.82 | 0.85–3.91 | 0.125 | 1.25 | 0.42–3.78 | 0.687 | 2.31 | 0.53–9.97 | 0.263 | 1.43 | 0.32–6.39 | 0.640 |
GnRH agonist ultra-long | 2.04 | 0.66–6.28 | 0.215 | 1.05 | 0.22–5.02 | 0.956 | 0.57 | 0.10–3.16 | 0.518 | 0.55 | 0.11–2.70 | 0.463 |
GnRH agonist short | 2.02 | 0.80–5.10 | 0.137 | 0.76 | 0.22–2.68 | 0.669 | 1.18 | 0.25–5.65 | 0.832 | 0.71 | 0.20–2.55 | 0.601 |
Duration of Gn | 1.14 | 0.94–1.39 | 0.182 | 0.78 | 0.56–1.08 | 0.134 | 0.88 | 0.59–1.30 | 0.513 | 1.16 | 0.81–1.64 | 0.417 |
Gn dose (per 100 IU) | 1.00 | 0.95–1.05 | 0.931 | 1.07 | 1.00–1.15 | 0.055 | 1.06 | 0.99–1.13 | 0.103 | 1.00 | 1.00–1.00 | 0.837 |
GH, growth hormone; BMI, body mass index; AMH, anti-Müllerian hormone; FSH, follicle-stimulating hormone; AFC, antral follicle count; COH, controlled ovarian hyperstimulation; GnRH, gonadotropin-releasing hormone; Gn, gonadotropin.
In bold: The values associated with GH.
*indicates statistical significances of p < 0.05.