Table 8.
Independent variable | POSEIDON group 1 | POSEIDON group 2 | POSEIDON group 3 | POSEIDON group 4 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
GH supplementation | ||||||||||||
Non-GH | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GH | 19.16 | 7.87–46.63 | <0.001* | 7.44 | 1.65–33.55 | 0.009* | 10.19 | 2.39–43.52 | 0.002* | 27.63 | 4.46–171.11 | <0.001* |
Age | 0.91 | 0.78–1.08 | 0.285 | 0.99 | 0.84–1.15 | 0.866 | 1.02 | 0.82–1.28 | 0.853 | 0.92 | 0.75–1.13 | 0.422 |
BMI | 0.94 | 0.84–1.06 | 0.346 | 1.02 | 0.88–1.18 | 0.800 | 1.24 | 1.03–1.50 | 0.027* | 1.07 | 0.83–1.37 | 0.598 |
AMH | 1.06 | 0.85–1.32 | 0.594 | 0.92 | 0.71–1.19 | 0.521 | 2.06 | 0.19–22.37 | 0.552 | 0.37 | 0.04–3.79 | 0.399 |
FSH | 0.86 | 0.67–1.11 | 0.254 | 1.13 | 0.89–1.43 | 0.308 | 0.91 | 0.70–1.18 | 0.456 | 0.66 | 0.44–0.97 | 0.034* |
AFC | 0.89 | 0.80–0.99 | 0.027* | 1.18 | 1.04–1.34 | 0.009* | 1.06 | 0.82–1.37 | 0.676 | 0.94 | 0.70–1.27 | 0.700 |
COH protocol | ||||||||||||
GnRH antagonist | _ | _ | _ | _ | _ | _ | _ | _ | ||||
GnRH agonist long | 1.52 | 0.62–3.73 | 0.359 | 0.61 | 0.18–2.02 | 0.418 | 1.30 | 0.27–6.29 | 0.748 | 1.80 | 0.31–10.38 | 0.508 |
GnRH agonist ultra-long | 1.53 | 0.44–5.31 | 0.506 | 0.43 | 0.08–2.40 | 0.338 | 0.51 | 0.08–3.22 | 0.470 | 0.36 | 0.05–2.66 | 0.318 |
GnRH agonist short | 1.51 | 0.49–4.70 | 0.472 | 0.77 | 0.18–3.36 | 0.732 | 0.82 | 0.14–4.95 | 0.832 | 1.50 | 0.30–7.44 | 0.621 |
Duration of Gn | 1.25 | 0.98–1.58 | 0.071 | 0.95 | 0.66–1.37 | 0.788 | 0.90 | 0.59–1.38 | 0.629 | 1.63 | 1.03–2.57 | 0.036* |
Gn dose (per 100 IU) | 0.98 | 0.92–1.04 | 0.522 | 1.01 | 0.93–1.09 | 0.863 | 1.06 | 0.99–1.15 | 0.112 | 1.00 | 1.00–1.00 | 0.491 |
GH, growth hormone; BMI, body mass index; AMH, anti-Müllerian hormone; FSH, follicle-stimulating hormone; AFC, antral follicle count; COH, controlled ovarian hyperstimulation; GnRH, gonadotropin-releasing hormone; Gn, gonadotropin.
In bold: The values associated with GH.
*indicates statistical significances of p < 0.05.