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. 2021 Dec 2;15:761473. doi: 10.3389/fnins.2021.761473

TABLE 3.

Epilepsy characteristics of seven patients.

ID 1 2 3 4 5 6 7
Age of seizure onset 37 months 30 months 30 months 10 months 26 months 25 months 30 months
Seizure type Myoclonic seizures, absence, falling seizures Eyelid myoclonia, myoclonic seizures with eyelid myoclonic Myoclonic seizures, West syndrome Eyelid myoclonia with atypical absences Eyelid myoclonia, falling seizures Absence with eyelid myoclonia, eyelid myoclonia Myoclonic seizures
Precipitating factors Weariness Eating (suspected) Eating Eating Crying
Status epilepticus
Seizure frequency 6–7/day 10 + /day 20 + /day 7–8/day 7–8/day 6–7/day 10–15/day
Alterations of seizure type + + + +
ASMs LEV-TPM-VPA LEV-VPA-ZNS LEV-VPA-CZP-ACTH-prednisone VPA-LEV-NZP VPA-LEV-LCM OXC-VPA (OXC discontinued) -LEV-NZP-CLB-LTG-KDT VPA-NZP-LEV
Seizure free + + +
Seizures at last follow-up Seizure-free for 24 months Seizure-free for 14 months Seizure-free for 18 months Seizure-free for 10 months Eyelid myoclonia Absence with eyelid myoclonia Myoclonus
EEG before seizure onset Abnormal Abnormal Normal Abnormal / Abnormal Abnormal
EEG, generalized spike and waves + + + + + +
EEG, multi-focal spike and waves + + + + + + +
EEG, hypsarrhythmia. + + +
Video-EEG Captured seizures Myoclonic seizures with absence. Myoclonic seizures, eyelid myoclonia, epileptic spasms. Epileptic spasms. Eyelid myoclonia. Epileptic spasms, myoclonic seizures. Atypical absence, eyelid myoclonia with absence, absence atonic seizures, focal seizures Epileptic spasms.

VPA, valproate; ZNS, zonisamide; LEV, levetiracetam; NZP, nitrazepam; CZP, clonazepam; CLB, clobazam; OXC, oxcarbazepine; LTG, lamotrigine; TPM, topiramate; ACTH, adrenocorticotropic hormone; KDT, ketogenic diet therapy; LCM, 1acosamide.