Table 3.
Clinical and radiological data of patients, sorted by attenuation value.
| HUm ≤10 | HUm >10 | p-value | |
|---|---|---|---|
| Age at diagnosis (years) | 65.5 ± 2.9 | 62.9 ± 4.1 | 0.068 |
| Gender female/male (% female) | 119/105 (53%) | 39/14 (74%) | 0.001 |
| Basal ACTH (ng/L) | 17.15 ± 12.3 | 15.15 ± 9.59 | 0.236 |
| Cortisol after 1-mg DST | 59.6 ± 51.9 | 94.2 ± 80.1 | <0.0001 |
| UFC (nmol/24 h) | 0.58 ± 0.22 | 0.59 ± 0.24 | 0.833 |
| HbA1c (mmol/mol) | 42.77 ± 9.23 | 41.7 ± 7.66 | 0.432 |
| BMI (kg/m2) | 29.61 ± 5.01 | 28.36 ± 5.36 | 0.197 |
| Mean diameter (mm) | 18.73 ± 6.98 | 18.71 ± 6.83 | 0.982 |
| Δ diameter (mm) | 0.8 ± 2.44 | 1.62 ± 2.77 | 0.044 |
| Δ attenuation value (HU) | −0.94 ± 7.84 | −5.43 ± 10.41 | 0.001 |
| HUm follow-up > baseline (%) | 96 (43%) | 17 (33%) | 0.203 |
| HUm follow-up < baseline (%) | 128 (57%) | 36 (67%) | |
| Hypertension (%) | 181 (81%) | 39 (73%) | 0.159 |
| Diabetes mellitus (%) | 45 (20%) | 12 (22%) | 0.645 |
| Dyslipidemia (%) | 101 (45%) | 23 (43%) | 0.767 |
| Osteoporosis (%) | 25 (11%) | 8 (15%) | 0.347 |
Data are presented as mean and standard deviation. NFAI, nonfunctioning adrenal incidentaloma; ACS, autonomous cortisol secretion; HUm, mean of Hounsfield unit in unenhanced CT; UFC, urinary free cortisol; BMI, body mass index; HbA1c, glycated hemoglobin; Δ, difference from baseline CT; DST, dexamethasone suppression test.