TABLE 4.
Price per pill of dual‐drug single pill combination (SPC) as compared with price of their corresponding component single agent pill (SAP) anti‐hypertensive medicines in the Indian private sector
| SPC | SAP 1 | SAP 2 | MRP range comparison | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 Drug SPC | Strengths | Drug classes | No. of brands analyzed | Median in INR (USD) | MRP range in INR (USD) | No. of brands analyzed* | Median in INR (USD) | MRP range in INR (USD) | No. of brands analyzed* | Median in INR (USD) | MRP range in INR (USD) | MRP range as single mol (SAP1+SAP2) in INR (USD) | Range comparison as combination drug in INR (USD) |
| Amlodipine + Atenolol | 5 MG/50 MG | CCB + BB | 6 | 4.99 (0.07) | 1.27–10.03 (0.02–0.14) | 10 | 2.80 (0.04) | 0.68–2.86 (0.01–0.03) | 4 | 1.96 (0.03) | 0.71–1.96 (0.01–0.03) | 1.39–4.82 (0.02–0.07) | 1.27–10.03 (0.02–0.14) |
| Hydrochlorothiazide + Telmisartan | 12.5 MG/40 MG | Diuretic + ARB | 12 | 9.08 (0.12) | 3.53–15.48 (0.05–0.21) | 8 | 1.02 (0.01) | 0.87–1.09 (0.01–0.01) | 12 | 7.19 (0.1) | 3.40–7.33 (0.05–0.1) | 4.27–8.42 (0.06–0.11) | 3.53–15.48 (0.05–0.21) |
| Amlodipine + Telmisartan | 5MG/40 MG | CCB + ARB | 13 | 10.7 (0.14) | 3.35–14.30 (0.05–0.19) | 10 | 2.80 (0.04) | 0.68–2.86 (0.01–0.04) | 12 | 7.19 (0.1) | 3.40–7.33 (0.05–0.1) | 4.08–10.19 (0.06–0.14) | 3.35–14.30 (0.05–0.19) |
| Hydrochlorothiazide + Losartan | 12.5 MG/50 MG | Diuretic + ARB | 7 | 6.38 (0.09) | 3.00–11.95 (0.04–0.16) | 8 | 1.02 (0.01) | 0.87–1.09 (0.01–0.01) | 10 | 4.60 (0.06) | 2.16–6.6 (0.03–0.09) | 3.03–7.69 (0.04–0.10) | 3.00–11.95 (0.04–0.16) |
| Amlodipine + Metoprolol | 5 MG/50 MG | CCB + BB | 10 | 10.7 (0.14) | 2.77–12.57 (0.04–0.17) | 10 | 2.80 (0.04) | 0.68–2.86 (0.01–0.04) | 7 | 6.31 (0.09) | 6.14–6.33 (0.08–0.09) | 6.82–9.19 (0.09–0.12) | 2.77–12.57 (0.04–0.17) |
| Chlortalidone + Telmisartan | 12.5 MG/40 MG | Diuretic + ARB | 10 | 10.28 (0.14) | 3.75–14.62 (0.05–0.19) | 7 | 5.79 (0.08) | 2–6.86 (0.02–0.09) | 12 | 7.19 (0.1) | 3.40–7.33 (0.05–0.1) | 5.40–14.19 (0.07–0.19) | 3.75–14.62 (0.05–0.2) |
SPCs/SPC strengths that had more than five brands contributing to 70% of their sale only were considered for price comparison with combined price of the SAPs to avoid skewing of data due to limited sample. Brands for SAPs are also chosen based on top brands that contribute upto 70% sales of the particular SAP. Exchange rate USD:INR 1:74.
Prices are in 2019–2020 Indian rupees.