TABLE 2.
Simple logistic regression analysis for predicting risk factors associated with hypertension in 65 children with non‐alcoholic fatty liver disease
| Hypertension | |||
|---|---|---|---|
| OR | 95% CI | p‐value | |
| Age (year) | 1.392 | 1.123–1.726 | .003 |
| Boys | 3.008 | 0.623–15.316 | .168 |
| BMI z‐score | 3.971 | 1.842–8.563 | <.001 |
| Obesity | 2.172 | 1.069–72.018 | .043 |
| Waist circumference (cm) | 1.124 | 1.056–1.197 | <.001 |
| WHtR | 1.136 | 1.017–1.269 | .024 |
| Central obesity | 3.200 | 0.370–27.697 | .291 |
| Total body fat (%) | 1.055 | 0.978–1.138 | .170 |
| Fat‐free mass (%) | 0.948 | 0.879–1.023 | .169 |
| FMI (fat mass/height[m] 2 ) | 1.405 | 1.124–1.756 | .003 |
| FFMI (fat free mass/ height[m] 2 ) | 1.444 | 1.141–1.828 | .002 |
| AST (IU/L) | 1.003 | 0.992–1.014 | .574 |
| ALT (IU/L) | 1.001 | 0.995–1.008 | .671 |
| Total bilirubin (mg/dl) | 1.938 | 0.233–16.137 | .541 |
| GGT (IU/L) | 1.021 | 1.004–1.038 | .016 |
| Uric acid (mg/dl) | 1.333 | 0.969–1.833 | .077 |
| Total cholesterol (mg/dl) | 1.007 | 0.992–1.022 | .382 |
| Triglyceride (mg/dl) | 1.007 | 0.999–1.014 | .089 |
| HDL‐C (mg/dl) | 1.005 | 0.935–1.080 | .894 |
| LDL‐C (mg/dl) | 1.012 | 0.991–1.034 | .260 |
| Dyslipidemia | 5.357 | 1.100–26.089 | .038 |
| Fasting plasma glucose (mg/dl) | 1.018 | 0.998–1.038 | .079 |
| Insulin (mIU/L) | 1.014 | 0.980–1.049 | .426 |
| HOMA‐IR | 1.124 | 0.973–1.297 | .112 |
| QUICKI | 0.743 | 0.564–0.981 | .036 |
| HbA1c (%) | 1.116 | 0.782–1.594 | .545 |
| Prediabetes + Diabetes mellitus | 1.621 | 0.528–4.973 | .398 |
| Metabolic syndrome | 12.564 | 3.098–50.952 | <.001 |
| MRI Liver FF (%) | 1.037 | 0.990–1.085 | .126 |
| MRI Pancreas FF (%) | 1.205 | 1.039–1.398 | .014 |
Note: Odds ratios of WHtR and QUICK were odds ratios for hypertension by every 0.01 increment of WHtR and QUICKI.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI z‐score, body mass index standard deviation score; CI, confidence interval; FF, fat fraction.; FFMI, fat‐free mass index; FMI, fat free mass index; GGT, γ‐glutamyl transferase; HbA1c, glycosylated hemoglobin; HDL‐C, high density lipoprotein cholesterol; HOMA‐IR, homeostatic model assessment for insulin resistance; LDL‐C, low density lipoprotein cholesterol; MRI, magnetic resonance imaging; OR, odds ratio; QUICKI, quantitative insulin‐sensitivity check index; WHtR, waist circumference to height ratio.