TABLE 4.
Multivariable analysis of postmenopausal hypertensive women with LVH
| Parameter | Model1 | Model2 | Model3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| β | P | OR (95% CI) | β | P | OR (95% CI) | β | P | OR (95% CI) | |
| FT | 7.577 | .569 | 1.952 (0.000, 4.014) | 9.694 | .732 | 2.247 (0.000, 9.504) | 9.556 | .717 | 1.936 (0.000, 3.226) |
| BioT | −0.187 | .740 | 0.829 (0.273, 2.514) | −0.280 | .817 | 0.744 (0.081, 6.821) | −0.280 | .803 | 0.826 (0.274, 2.484) |
| FAI | 1.537 | .000 | 4.654 (3.098, 6.975) | 1.101 | .000 | 3.006 (1.930, 4.681) | 0.733 | .001 | 2.082 (1.067, 4.064) |
| SHBG | −0.059 | .000 | 0.943 (0.917, 0.970) | −0.055 | .000 | 0.950 (0.924, 0.978) | −0.051 | .001 | 0.948 (0.920, 0.976) |
| mTOR | 0.012 | .232 | 1.013 (0.992, 1.033) | 0.009 | .416 | 1.013 (0.991, 1.035) | 0.014 | .237 | 1.015 (0.992, 1.037) |
| PS6K1 | 0.096 | .160 | 1.101 (0.963, 1.259) | 0.112 | .114 | 1.108 (0.959, 1.280) | 0.095 | .220 | 1.113 (0.959, 1.292) |
Model 1: no adjustment; Model 2: adjusted for the course of hypertension, family history of hypertension, antihypertensive drugs, and serological indexes (TC); Model 3: Model 1+ Model 2+ the 24‐hour mean SBP+24‐hour mean DBP.
Abbreviations: Bio T, bioavailable testosterone; DBP, diastolic blood pressure; FT, free testosterone; FAI, free androgen index; SBP, systolic blood pressure; SHBG, sex hormone–binding globulin; mTOR, mammalian target of rapamycin; PS6K, phosphorylated ribosome S6 protein kinase.