TABLE 4.

Effects of lowering blood pressure by the HERB intervention

	Mean changes at 16 weeks				Mean changes at 24 weeks
	Intervention	Controls	Adjusted difference [95% CI]	p‐Value a	Intervention	Controls	Adjusted difference [95% CI]	p‐Value a
SBP
ABPM 24 hours	0.096	−0.29	0.35 [−4.3 to 5.0]	.88	−0.47	−0.042	−0.66 [−5.3 to 3.9]	.78
ABPM daytime	1.6	2.5	−0.90 [−5.6 to 3.8]	.71	2.1	2.1	−0.11 [−5.0 to 4.8]	.97
ABPM nighttime	−1.9	−3.4	1.3 [−4.2 to 6.9]	.64	−4.1	−1.9	−2.6 [−7.9 to 2.7]	.33
Office	−6.3	−2.8	−3.4 [−8.5 to 1.6]	.18	−9.4	−5.5	−3.4 [−8.8 to 1.9]	.21
Home	−4.1	−0.96	−3.1 [−6.3 to 0.11]	.06	−5.2	−2.0	−3.1 [−6.4 to 0.26]	.07
DBP
ABPM 24 hours	−0.15	−0.32	0.14 [−2.4 to 2.7]	.92	−1.3	−0.20	−1.1 [−3.7 to 1.4]	.39
ABPM daytime	1.0	0.92	0.066 [−2.6 to 2.8]	.96	0.38	0.38	0.001 [−2.9 to 2.9]	1.00
ABPM nighttime	−1.5	−1.1	−0.44 [−3.6 to 2.7]	.79	−3.2	−0.042	−3.3 [−6.3 to − 0.19]	.04
Office	−3.7	−2.6	−1.1 [−3.9 to 1.7]	.43	−5.7	−4.1	−1.6 [−4.8 to 1.7]	.35
Home	−2.4	−0.81	−1.5 [−3.8 to 0.74]	.19	−3.2	−2.2	−0.73 [−3.3 to 1.8]	.58
Pulse pressure	0.25	0.028	0.22 [−2.3 to 2.7]	.87	0.78	0.15	0.46 [−2.2 to 3.1]	.73
Body weight	−0.059	−0.26	0.19 [−0.42 to 0.81]	.54	0.18	−0.10	0.26 [−0.44 to 0.95]	.47
BMI	−0.022	−0.093	0.068 [−0.15 to 0.29]	.55	0.052	−0.034	0.079 [−0.17 to 0.33]	.54
Waist circumference	0.14	0.15	−0.021 [−1.1 to 1.0]	.97	−0.59	−0.38	−0.17 [−1.2 to 0.88]	.75

Abbreviations: ABPM, ambulatory blood pressure monitoring; DBP, diastolic blood pressure; SBP, systolic blood pressure.

^a Calculated by an ANCOVA adjusted by the use of antihypertensive medications and the mean outside temperature on the day of ABPM measurement.