FIGURE 3.

Scatter plot for the interrelationship between the changes in systolic blood pressure and that in plasma concentration of serotonin (left panel) and norepinephrine (right panel) by randomization group. Regression lines were drawn for the quadruple combination (dots with solid line) and placebo groups (circles with dashed line) separately. Pearson correlation coefficients (r) and the corresponding p values are given alongside the regression line. The numbers of patients per group and the p value for interaction between randomization group and changes in plasma concentration of serotonin or norepinephrine in relation to the changes in systolic blood pressure (p _int) are also given