TABLE 4.
Regression model controlling for systolic blood pressure and detectible serum lisinopril at week 52
R 2 | Week 52 SBP | Lisinopril | |||||
---|---|---|---|---|---|---|---|
Estimate | 95% Conf. Limits | p‐Value | Estimate | 95% Conf. Limits | p‐Value | ||
LVMI (g/m2) | .1342 | 0.2636 | [0.085, 0.442] | .004 | ‐0.5463 | [−6.911, 5.818] | .864 |
PICP/CITP | .0237 | 0.3126 | [−0.255, 0.88] | .275 | 8.603 | [−11.628, 28.834] | .399 |
PICP | .0704 | 0.4603 | [0.039, 0.881] | .032 | 4.9843 | [−10.029, 19.998] | .509 |
CITP | .0057 | 0.0095 | [−0.032, 0.051] | .653 | ‐0.1895 | [−1.683, 1.304] | .801 |
MMP‐1/TIMP‐1 | .1191 | ‐0.0002 | [−0.001, 0] | .186 | 0.0139 | [0, 0.027] | .043 |
MMP‐1 | .0893 | ‐0.0371 | [−0.089, 0.015] | .156 | 1.4337 | [−0.411, 3.278] | .125 |
TIMP‐1 | .0274 | ‐0.0235 | [−0.54, 0.493] | .927 | ‐11.9787 | [−30.375, 6.417] | .198 |
Ac‐SDKP | .1666 | 0.0148 | [−0.025, 0.054] | .456 | 2.4915 | [1.085, 3.898] | .001 |
Abbreviations: Ac‐SDKP, N‐acetyl‐seryl‐aspartyl‐lysyl‐proline; CITP, telopeptide of collagen type I; LVMI, Left ventricular mass‐Indexed; MMP‐1, matrix metalloproteinase‐1; PICP, type 1 procollagen C‐terminal propeptide; TIMP‐1, tissue inhibitor of metalloproteinases 1.