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. 2021 Mar 10;23(5):1008–1016. doi: 10.1111/jch.14206

TABLE 4.

Regression model controlling for systolic blood pressure and detectible serum lisinopril at week 52

R 2 Week 52 SBP Lisinopril
Estimate 95% Conf. Limits p‐Value Estimate 95% Conf. Limits p‐Value
LVMI (g/m2) .1342 0.2636 [0.085, 0.442] .004 ‐0.5463 [−6.911, 5.818] .864
PICP/CITP .0237 0.3126 [−0.255, 0.88] .275 8.603 [−11.628, 28.834] .399
PICP .0704 0.4603 [0.039, 0.881] .032 4.9843 [−10.029, 19.998] .509
CITP .0057 0.0095 [−0.032, 0.051] .653 ‐0.1895 [−1.683, 1.304] .801
MMP‐1/TIMP‐1 .1191 ‐0.0002 [−0.001, 0] .186 0.0139 [0, 0.027] .043
MMP‐1 .0893 ‐0.0371 [−0.089, 0.015] .156 1.4337 [−0.411, 3.278] .125
TIMP‐1 .0274 ‐0.0235 [−0.54, 0.493] .927 ‐11.9787 [−30.375, 6.417] .198
Ac‐SDKP .1666 0.0148 [−0.025, 0.054] .456 2.4915 [1.085, 3.898] .001

Abbreviations: Ac‐SDKP, N‐acetyl‐seryl‐aspartyl‐lysyl‐proline; CITP, telopeptide of collagen type I; LVMI, Left ventricular mass‐Indexed; MMP‐1, matrix metalloproteinase‐1; PICP, type 1 procollagen C‐terminal propeptide; TIMP‐1, tissue inhibitor of metalloproteinases 1.