TABLE 2.
Clinical characteristics of women in the aspirin group vs. control group with normotension or stage 1 hypertension when initialed at or before 16 weeks of gestation
| Normotension | Stage 1 hypertension | |||||
|---|---|---|---|---|---|---|
| Control | Aspirin | p value | Control | Aspirin | p value | |
| 95 | 95 | 49 | 44 | |||
| Age (years) | 32.5 ± 4.3 | 32.8 ± 4.8 | .705 | 32.5 ± 4.1 | 32.1 ± 4.6 | .627 |
| Prepregnancy BMI (kg/cm2) | 24.9 ± 4.1 | 24.8 ± 3.9 | .857 | 26.2 ± 4.1 | 24.5 ± 4.3 | .063 |
| Advanced age, n (%) | 36 (37.9) | 37 (38.9) | .881 | 20 (40.8) | 12 (27.3) | .170 |
| Obesity, n (%) | 27 (28.4) | 24 (25.3) | .623 | 16 (32.7) | 13 (29.5) | .747 |
| Preexisting diabetes, n (%) | 37 (38.9) | 34 (35.8) | .653 | 21 (42.9) | 18 (40.9) | .849 |
| PE history, n (%) | 34 (35.8) | 36 (37.9) | .764 | 20 (40.8) | 19 (43.2) | .817 |
| Nulliparity, n (%) | 43 (45.3) | 36 (37.9) | .303 | 14 (28.6) | 8 (18.2) | .239 |
| Family history of PE, n (%) | 4 (4.2) | 2 (2.1) | .407 | 2 (4.1) | 1 (2.3) | .622 |
| SBP at enrollment (mmHg) | 113.5 ± 8.3 | 114.9 ± 7.8 | .253 | 127.0 ± 7.9 | 123.8 ± 7.6 | .055 |
| DBP at enrollment (mmHg) | 68.6 ± 6.6 | 68.6 ± 6.0 | .945 | 83.1 ± 5.5 | 82.4 ± 3.7 | .486 |
| Gestational age at delivery (week) | 37.8 ± 3.2 | 38.1 ± 2.8 | .512 | 37.4 ± 3.4 | 38.6 ± 1.2 | .042 |
| Birth weight (g) | 3145.1 ± 745.4 | 3195.7 ± 646.1 | .638 | 3123.8 ± 678.5 | 3335.0 ± 631.0 | .154 |
Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure.