TABLE 3.
The aspirin effect on pregnancy outcomes initiated at or before 16 weeks of gestation in women with stage 1 hypertension or normotension
| Normotension | Stage 1 hypertension | |||||||
|---|---|---|---|---|---|---|---|---|
|
Control 95 |
Aspirin 95 |
aOR (95% CI) | p value |
Control 49 |
Aspirin 44 |
aOR (95% CI) | p value | |
| Preeclampsia, n (%) | 6 (6.3) | 4 (4.2) | 0.511 (0.121–2.159) | .361 | 10 (20.4) | 2 (4.5) | 0.139 (0.027–0.716) | .018 |
| Delivery at <37 gestational weeks | 4 (4.2) | 1 (1.1) | 0.247 (0.026–2.344) | .223 | 5 (10.2) | 1 (2.3) | 0.105 (0.010–1.137) | .064 |
| Delivery at ≥37 gestational weeks | 2 (2.1) | 3 (3.2) | 1.095 (0.147–8.176) | .929 | 5 (10.2) | 1 (2.3) | 0.184 (0.020–1.703) | .136 |
| Preterm birth, n (%) | 17 (17.9) | 10 (10.5) | 0.506 (0.212–1.210) | .126 | 9 (18.4) | 2 (4.5) | 0.141 (0.025–0.782) | .025 |
| Placental abruption, n (%) | 9 (9.5) | 9 (9.5) | 1.030 (0.384–2.760) | .953 | 3 (6.1) | 4 (9.1) | 2.076 (0.346–12.457) | .424 |
| Postpartum hemorrhage, n (%) | 9 (9.5) | 9 (9.5) | 0.871 (0.312–2.437) | .793 | 1 (2.0) | 4 (9.1) | 6.264 (0.602–65.171) | .125 |
| SGA (<10th percentile), n (%) | 5 (5.3) | 9 (9.5) | 2.101 (0.668–6.608) | .204 | 4 (8.2) | 2 (4.5) | 0.489 (0.082–2.904) | .431 |
Abbreviations: aOR, adjusted odds ratio, adjusted for maternal age, prepregnancy body mass index, nulliparity; CI, confidence interval; NA, not applicable; SGA, small for gestational age.