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. 2021 Jan 5;23(5):1060–1067. doi: 10.1111/jch.14149

TABLE 3.

The aspirin effect on pregnancy outcomes initiated at or before 16 weeks of gestation in women with stage 1 hypertension or normotension

Normotension Stage 1 hypertension

Control

95

Aspirin

95

aOR (95% CI) p value

Control

49

Aspirin

44

aOR (95% CI) p value
Preeclampsia, n (%) 6 (6.3) 4 (4.2) 0.511 (0.121–2.159) .361 10 (20.4) 2 (4.5) 0.139 (0.027–0.716) .018
Delivery at <37 gestational weeks 4 (4.2) 1 (1.1) 0.247 (0.026–2.344) .223 5 (10.2) 1 (2.3) 0.105 (0.010–1.137) .064
Delivery at ≥37 gestational weeks 2 (2.1) 3 (3.2) 1.095 (0.147–8.176) .929 5 (10.2) 1 (2.3) 0.184 (0.020–1.703) .136
Preterm birth, n (%) 17 (17.9) 10 (10.5) 0.506 (0.212–1.210) .126 9 (18.4) 2 (4.5) 0.141 (0.025–0.782) .025
Placental abruption, n (%) 9 (9.5) 9 (9.5) 1.030 (0.384–2.760) .953 3 (6.1) 4 (9.1) 2.076 (0.346–12.457) .424
Postpartum hemorrhage, n (%) 9 (9.5) 9 (9.5) 0.871 (0.312–2.437) .793 1 (2.0) 4 (9.1) 6.264 (0.602–65.171) .125
SGA (<10th percentile), n (%) 5 (5.3) 9 (9.5) 2.101 (0.668–6.608) .204 4 (8.2) 2 (4.5) 0.489 (0.082–2.904) .431

Abbreviations: aOR, adjusted odds ratio, adjusted for maternal age, prepregnancy body mass index, nulliparity; CI, confidence interval; NA, not applicable; SGA, small for gestational age.