TABLE 3.
Association between age with indices of cardiac and arterial structure and function
| Per 10 years increase in age | β‐coefficient (95% confidence interval) | ||
|---|---|---|---|
| Men | Women | p‐Interaction | |
| Left atrial volume index (ml/m2) | 1.53 (−0.34, 3.40) | 0.97 (−0.55, 2.48) | .637 |
| Septal e′ velocity (cm/s) | −0.55 (−0.68, −0.41) | −0.74 (−0.85, −0.63) | .029 |
| Septal E/e′ ratio | 0.36 (−0.08, 0.80) | 1.39 (1.01, 1.77) | <.001 |
| Left ventricular mass index (g/m2) | 1.64 (−0.44, 3.71) | 2.04 (0.31, 3.76) | .768 |
| LVMV ratio (g/ml) | 0.004 (−0.020, 0.028) | 0.004 (−0.024, 0.031) | .988 |
| LVEF (%) | 0.06 (−0.53, 0.64) | −0.31 (−0.84, 0.22) | .36 |
| SV index (ml/m2) | 0.60 (−0.37, 1.57) | −0.01 (−0.91, 0.89) | .364 |
| Septal S′ (m/s) | −0.30 (−0.42, −0.19) | −0.47 (−0.58, −0.36) | .038 |
| Ees (mm Hg/ml) | 0.06 (−0.10, 0.21) | 0.24 (0.11, 0.36) | .071 |
| Eed (mm Hg/ml) | 0.006 (0.001, 0.010) | 0.016 (0.01, 0.020) | .004 |
| Ea (mm Hg/ml) | 0.04 (−0.02, 0.10) | 0.13 (0.07, 0.18) | .038 |
| Ea/Ees ratio | 0.010 (−0.012, 0.032) | 0.001 (−0.014, 0.017) | .501 |
| Pulse pressure (mm Hg) | 3.10 (1.98, 4.23) | 3.91 (2.87, 4.95) | .303 |
| Per 10 years increase in age | Adjusted β‐coefficient (95% confidence interval) | ||
|---|---|---|---|
| Men | Women | p‐interaction | |
| Left atrial volume index (ml/m2) | 3.29 (1.02, 5.57) | 2.30 (0.61, 4.00) | .358 |
| Septal e′ velocity (cm/s) | −0.64 (−0.80, −0.49) | −0.74 (−0.87, −0.61) | .115 |
| Septal E/e′ ratio | 0.66 (0.14, 1.18) | 1.45 (1.00, 1.89) | .001 |
| Left ventricular mass index (g/m2) | 1.61 (−0.91, 4.13) | 2.14 (0.13, 4.14) | .805 |
| LVMV ratio (g/ml) | 0.004 (−0.023, 0.032) | 0.007 (−0.026, 0.040) | .603 |
| LVEF (%) | −0.26 (−0.99, 0.47) | −0.39 (−1.02, 0.24) | .225 |
| SV index (ml/m2) | 0.27 (−0.95, 1.49) | −0.15 (−1.22, 0.92) | .219 |
| Septal S′ (m/s) | −0.27 (−0.41, −0.13) | −0.45 (−0.58, −0.32) | .048 |
| Ees (mm Hg/ml) | −0.02 (−0.22, 0.17) | 0.18 (0.04, 0.33) | .064 |
| Eed (mm Hg/ml) | 0.006 (0, 0.012) | 0.014 (0.009, 0.019) | .002 |
| Ea (mm Hg/ml) | 0.03 (−0.04, 0.11) | 0.12 (0.06, 0.18) | .005 |
| Ea/Ees ratio | 0.020 (−0.010, 0.040) | 0.002 (−0.020, 0.020) | .634 |
| Pulse pressure (mm Hg) | 3.23 (1.85, 4.62) | 4.06 (2.83, 5.30) | .274 |
Adjusting for smoking, body mass index, waist/hip ratio, diabetes mellitus, eGFR, uric acid and antihypertensive drugs.
Abbreviations: Ea, effective arterial elastance; Eed, left ventricular end‐diastolic elastance; Ees, left ventricular end‐systolic elastance; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; LVMV, left ventricular mass‐to‐volume; SV, stroke volume.