TABLE 4.
Impacts of the achieved SBP level on age‐related changes in selected indices of cardiac and arterial structure and function
| Per 10 years increase in age | Adjusted β‐coefficient (95% confidence interval) | ||
|---|---|---|---|
| SBP <130 mm Hg | Men (n = 110) | Women (n = 195) | p‐Interaction |
| Septal S′ (m/s) | −0.58 (−0.82, −0.34) | −0.39 (−0.60, −0.18) | .569 |
| Septal E/e′ ratio | 1.01 (0.39, 1.62) | 1.27 (0.40, 2.15) | .325 |
| Ea (mm Hg/ml) | −0.02 (−0.13, 0.08) | 0.12 (0.06, 0.18) | .488 |
| Eed (mm Hg/ml) | 0.006 (−0.003, 0.015) | 0.011 (0.001, 0.021) | .286 |
| SBP ≥130 mm Hg | Men (n = 259) | Women (n = 407) | p‐Interaction |
| Septal S′ (m/s) | −0.13 (−0.31, 0.05) | −0.45 (−0.62, −0.29) | .014 |
| Septal E/e′ ratio | 0.48 (−0.23, 1.18) | 1.42 (0.89, 1.94) | .003 |
| Ea (mm Hg/ml) | 0.05 (−0.04, 0.14) | 0.14 (0.07, 0.22) | .019 |
| Eed (mm Hg/ml) | 0.005 (−0.003, 0.012) | 0.016 (0.009, 0.022) | .002 |
| SBP <140 mm Hg | Men (n = 220) | Women (n = 354) | p‐Interaction |
| Septal S′ (m/s) | −0.30 (−0.48, −0.12) | −0.50 (−0.69, −0.32) | .197 |
| Septal E/e′ ratio | 0.38 (−0.36, 1.12) | 1.26 (0.67, 1.85) | .026 |
| Ea (mm Hg/ml) | 0.01 (−0.06, 0.09) | 0.06 (−0.01, 0.13) | .184 |
| Eed (mm Hg/ml) | 0.004 (−0.004, 0.012) | 0.011 (0.004, 0.018) | .067 |
| SBP ≥140 mm Hg | Men (n = 149) | Women (n = 248) | p‐Interaction |
| Septal S′ (m/s) | −0.21 (−0.45, 0.04) | −0.36 (−0.54, −0.17) | .082 |
| Septal E/e′ ratio | 1.22 (0.59, 1.85) | 1.65 (0.96, 2.34) | .049 |
| Ea (mm Hg/ml) | 0.08 (−0.06, 0.21) | 0.16 (0.06, 0.26) | .034 |
| Eed (mm Hg/ml) | 0.011 (0.003, 0.019) | 0.018 (0.009, 0.026) | .016 |
Adjusting for smoking, body mass index, waist/hip ratio, diabetes mellitus, eGFR, uric acid and antihypertensive drugs.
Abbreviations: Ea, effective arterial elastance; Eed, left ventricular end‐diastolic elastance; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure.