Table 2.
Serum pepsinogen I, pepsinogen II, pepsinogen ratio, and gastrin-17 values for patient subgroups stratified by bleeding complication and ulcer type
Group
|
Number of cases (n)
|
PGI (μg/L)
|
PGII (μg/L)
|
PGR (PGI/II)
|
G-17 (pmol/L)
|
|
Peptic ulcer group | GU | 45 | 197.90 ± 89.97 | 20.40 ± 13.70 | 11.46 ± 4.70 | 7.24 ± 8.43 |
DU | 49 | 224.43 ± 80.60 | 23.19 ± 17.05 | 12.58 ± 5.33 | 9.17 ± 6.33 | |
CU | 13 | 220.48 ± 107.82 | 24.09 ± 10.16 | 10.70 ± 5.86 | 13.11 ± 10.91 | |
Total | 107 | 225.86 ± 91.10 | 21.68 ± 14.47 | 12.74 ± 5.51 | 13.03 ± 13.20 | |
Peptic ulcer complicated with upper gastrointestinal bleeding group | GU | 20 | 240.52 ± 83.47 | 22.10 ± 15.30 | 15.15 ± 13.20 | 26.13 ± 13.68a |
DU | 64 | 250.64 ± 85.70 | 19.22 ± 10.71 | 14.91 ± 5.32 | 25.84 ± 15.00a | |
CU | 8 | 238.55 ± 95.15 | 18.30 ± 7.51 | 14.70 ± 6.31 | 19.32 ± 8.87 | |
Total | 92 | 234.98 ± 90.67 | 19.65 ± 12.25 | 14.44 ± 7.39 | 25.34 ± 14.29a |
P < 0.01 compared to the corresponding non-bleeding group.
PGI: Pepsinogen I; PGII: Pepsinogen II; PGR: PGI/PGII ratio; G-17: Gastrin-17; GU: Gastric ulcer; DU: Duodenal ulcer; CU: Complex ulcer.