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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Histopathology. 2021 Sep 5;79(5):836–846. doi: 10.1111/his.14433

Table 2.

Univariate survival analysis of radiation-associated angiosarcomas

Variables OS DSS LRFS DMFS
Univariate Cox proportional model P value
Age (continuous variable) 0.047 0.021 0.027 0.003
Tumor size (continuous variable) 0.012 0.028 0.037 0.049
Log-rank P value
Margin status a : positive vs. negative 0.002 0.003 <0.001 0.911
MYC amplification: amplified vs. non-amplified 0.029 0.069 0.372 0.117
Chemotherapy: no chemotherapy vs. adjuvant chemotherapy vs. neoadjuvant chemotherapy 0.819 0.805 0.422 0.266
Adjuvant radiation: yes vs. no 0.352 0.871 0.234 0.269

OS=overall survival; DSS= disease specific survival; LRFS=local recurrence free survival; DMFS=distant metastasis free survival;

a

only microscopic margin status included