Figure 2. Diagnostic Yield and Distribution of Genes With Molecular Diagnoses by Age at Seizure Onset.

(A) The proportion of individuals with a definitive molecular diagnosis was calculated based on age at seizure onset (age groups defined in x-axis). (B) Among those with a definitive molecular diagnosis, the number of individuals with diagnostic findings in each gene was stratified according to age at seizure onset (age groups defined in the legend). These analyses included only individuals with a noted numerical age at onset. ^aA pathogenic copy number variant spanning both genes was observed as a single event.