. 2021 Nov 30;143(49):20598–20604. doi: 10.1021/jacs.1c10245

Table 2. Substrate Scope^a.

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0.25 mmol of substrate 1, 2–3 equiv of paraformaldehyde 2a, and 2.5 mol % of catalyst 4b, in 2.5 mL of dry cyclohexane (0.1 M) at 25 °C for 72 h, unless otherwise stated.

Using catalyst 4b′.

Using catalyst 4c.

Using catalyst 4d.

Using catalyst 4e.

Concentration: 0.2 M.

Concentration: 0.05 M.

Concentration: 0.025 M.

ⁱ

Reaction for 96 h.

Reaction for 5 days. See the Supporting Information for further details.

Table 2. Substrate Scopea.

Table 2. Substrate Scope^a.